Pittsburgh vs. Louisville CBB Predictions and Odds - Jan 5, 2022

Louisville and Pittsburgh meet in College Basketball action at KFC Yum! Center on Wednesday, with tipoff at 7:00PM EST.

Dimers' best betting picks for Pittsburgh vs. Louisville, plus game predictions and best odds, are featured below.

Who will win Pittsburgh vs. Louisville?

Based on high-tech machine learning and data, Dimers.com has simulated Wednesday's Pittsburgh-Louisville NCAA Basketball game 10,000 times.

Dimers' popular predictive analytics model, DimersBOT, gives Louisville an 86% chance of beating Pittsburgh.

MORE: Free Betting Guide for Pittsburgh vs. Louisville

Point Spread, Moneyline and Over/Under

Louisville is the -12.5 favorite against Pittsburgh, with -105 at PointsBet the best odds available.

For the underdog Pittsburgh (+12.5) to cover the spread, BetMGM has the best odds on the market at -110.

PointsBet has the best moneyline odds for Louisville at -740. That means you can risk $740 to win $100, for a total payout of $840, if it gets the W.

Elsewhere, FanDuel Sportsbook has the best moneyline odds for Pittsburgh at +590, where you can bet $100 to profit $590, earning a total payout of $690, if it wins.

The Over/Under for total points scored is set at 131.5 with BetMGM, which has the best odds for the Over at -110, while DraftKings Sportsbook has the best odds for the Under at -105.

As always, check out all the online sportsbooks that are available in your state for the best College Basketball odds and lines.

According to DimersBOT, Pittsburgh (+12.5) is a 61% chance of covering the spread, while the Over/Under total of 131.5 points is a 51% chance of going Under.

MORE: Predictions for Every College Basketball Matchup

Best Bets for Pittsburgh vs. Louisville

• Spread: Pittsburgh +12.5 at -110 with BetMGM (61% probability) 🔥
• Moneyline: Louisville Win at -740 with PointsBet (86% probability)
• Over/Under: Under 131.5 at -105 with DraftKings Sportsbook (51% probability)

If you see a 🔥, that means it's one of Dimers' best free picks today across all sports.

Pittsburgh vs. Louisville Score Prediction

Dimers.com's predicted final score for Pittsburgh vs. Louisville at KFC Yum! Center on Wednesday has Louisville winning 70-60.

Use our widget below to view the current Spread, Over/Under and Moneyline probabilities and odds for the game, and click or tap on See Matchup to reveal more.

Dimers has full betting coverage of Wednesday's Pittsburgh-Louisville matchup, including pre-game predictions, top betting picks, and live win probabilities.

Don't forget, DimersBOT updates frequently, so refresh this article for any changes to our betting analysis before Pittsburgh vs. Louisville on Wednesday January 5, 2022.

Best Sportsbook Promo for Pittsburgh vs. Louisville

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Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.

Pittsburgh vs. Louisville 2022 CBB Game Info

When does Louisville play Pittsburgh in College Basketball?

• Date: Wednesday January 5, 2022
• Time: 7:00PM EST / 4:00PM PST
• Venue: KFC Yum! Center

Ready to join an online sportsbook and start betting on College Basketball? We've reviewed the best available sign-up offers for each legal betting state.

What College Basketball games are on tonight?

Now you've got the 411 on Pittsburgh vs. Louisville, see the latest betting coverage for all upcoming NCAA Basketball games in Dimers' College Basketball Bet Hub, where you can find probabilities and odds, and our best bets for each and every CBB matchup.

Want a pick for the Spread? You got it. How about the Over/Under? Yup, got that too. The Moneyline? Yes sir. And these picks are good, I mean REALLY good. Take a look now!