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Pirates vs. Diamondbacks prediction: Why Arizona is favored to win Thursday's MLB matchup [5/7/2026]

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Written by Dave Garofolo

Get Pittsburgh Pirates vs Arizona Diamondbacks predictions for MLB Thursday.

Pittsburgh Pirates-Arizona Diamondbacks Predictions and Game Preview.
Pittsburgh Pirates vs. Arizona Diamondbacks MLB prediction for Thursday, May 7, 2026.

The Arizona Diamondbacks and Pittsburgh Pirates will lock horns in MLB action at Chase Field on Thursday, starting at 3:40 PM ET.

The Diamondbacks will send Zac Gallen (1-2, 4.45 ERA) to the mound, pitting him against Mitch Keller (3-1, 2.85 ERA) for the Pirates.

Based on the latest simulation results, Dimers' proven MLB model gives the Diamondbacks a slight edge with a 54% win probability over the Pirates.

This article offers an expanded analysis of Thursday's Pirates vs. Diamondbacks matchup, including best bets and picks.

Pirates vs. Diamondbacks prediction: Who will win?

Using innovative machine learning and data, we have simulated the outcome of Thursday's MLB game between the Pirates and Diamondbacks, forming part of our MLB predictions coverage.

Our leading predictive model gives the Diamondbacks a 54% chance of defeating the Pirates.

According to our model, the over/under total of nine runs has a 56% chance of going over.

 

Pirates vs. Diamondbacks odds [5/7/2026]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type Pirates Diamondbacks
Moneyline -103 -112
Total o9 (-101) u9 (-129)

All odds are correct at the time of publication and are subject to change.

Pirates vs. Diamondbacks picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Moneyline Diamondbacks -112
Total Over 9 -101

According to our MLB best bets, the top play to make on this game is Over 9 total runs.

These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.

 

Pirates vs. Diamondbacks game-day updates and essential details

Thursday's MLB game between the Diamondbacks and Pirates at Chase Field is scheduled to begin at 3:40 PM ET.

Conclusion

We predict the Diamondbacks, with a 54% win probability, will likely beat the Pirates in Thursday's MLB matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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