Pirates vs. Tigers Prediction and Odds - May 4, 2022

The Detroit Tigers face the Pittsburgh Pirates in MLB action at Comerica Park on Wednesday, starting at 1:10PM ET.

The Tigers will send Tarik Skubal (1-2, 3.05 ERA) to the mound, while the Pirates will counter with José Quintana (0-1, 3.32 ERA).

Dimers' best betting picks for Pirates vs. Tigers, plus game predictions and best odds, are featured below.

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Who will win Pirates vs. Tigers?

Using advanced computer power and data, Dimers.com has simulated Wednesday's Pirates-Tigers MLB matchup 10,000 times.

Dimers' renowned predictive analytics model, DimersBOT, currently gives the Tigers a 60% chance of defeating the Pirates.

More: Full Betting Analysis for Pirates vs. Tigers

Pirates vs. Tigers Game Odds

• Run Line: Tigers -1.5 (+160), Pirates +1.5 (-169)
• Moneyline: Tigers -134, Pirates +120
• Total: Over/Under 7.5 (-114/+105)

Run Line, Moneyline and Over/Under

The Tigers are -1.5 favorites versus the Pirates, with +160 at DraftKings Sportsbook the best odds currently available.

For the underdog Pirates (+1.5) to cover the run line, Caesars Sportsbook has the best odds currently on offer at -169.

FanDuel Sportsbook currently has the best moneyline odds for the Tigers at -134. That means you can risk $134 to win $100, for a total payout of $234, if they get the W.

Elsewhere, DraftKings Sportsbook currently has the best moneyline odds for the Pirates at +120, where you can bet $100 to profit $120, earning a total payout of $220, if they win.

The Over/Under for total runs scored sits at 7.5 with FanDuel Sportsbook, which currently has the best odds for the Over at -114, while PointsBet currently has the best odds for the Under at +105.

As always, make sure you check the sportsbooks you have access to in your state for the best MLB odds and lines.

According to DimersBOT, the Pirates (+1.5) are a 59% chance of covering the run line, while the 7.5-run Over/Under is a 57% chance of going Over.

More: Best Bets for Every MLB Matchup

Best Bets for Pirates vs. Tigers

• Run Line: Tigers -1.5 @ +160 via DraftKings Sportsbook (3.0% edge)
• Moneyline: Tigers @ -134 via FanDuel Sportsbook (60% probability)
• Total: Over 7.5 @ -114 via FanDuel Sportsbook (57% probability)

Dimers' best bets are based on world-class simulations and wagering intelligence to bring you the best possible plays every time.

Although the Pirates are more likely to cover the run line, our best bet of Tigers -1.5 is based on the chance of that happening, according to DimersBOT, and the best odds available.

Pirates vs. Tigers Betting Guide

Use our interactive widget below to explore the latest Moneyline, Over/Under and Run Line probabilities and odds for Pittsburgh vs. Detroit, and click or tap on See Matchup for more.

Dimers has full coverage of Wednesday's Pirates-Tigers matchup, including pregame predictions, free picks, and live updates.

Don't forget, DimersBOT updates frequently, so refresh this page for the latest betting insights before Pirates vs. Tigers on Wednesday May 4, 2022.

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Pirates vs. Tigers 2022 Game Info

When do the Tigers play the Pirates?

• Date: Wednesday May 4, 2022
• Time: 1:10PM ET / 10:10AM PT
• Venue: Comerica Park

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