Pirates vs. Cubs Prediction and Odds - May 17, 2022

The Chicago Cubs square off with the Pittsburgh Pirates at Wrigley Field on Tuesday, commencing at 7:40PM ET.

The Cubs will send Keegan Thompson (2-0, 1.67 ERA) to the mound, pitting him against JT Brubaker (0-3, 5.34 ERA) for the Pirates.

Dimers' best betting picks for Pirates vs. Cubs, plus game predictions and best odds, are featured below.

This Pittsburgh vs. CHI Cubs betting analysis is proudly sponsored by PointsBet, which has an outstanding 5x $100 Risk-Free Bets offer for new users.

Who will win Pirates vs. Cubs?

Based on trusted computer power and data, Dimers.com has simulated Tuesday's Pirates-Cubs MLB matchup 10,000 times.

Dimers' revolutionary predictive analytics model, DimersBOT, gives the Cubs a 56% chance of defeating the Pirates .

More: Pirates vs. Cubs Simulated 10K Times

Pirates vs. Cubs Current Odds

• Run Line: Cubs -1.5 (+150), Pirates +1.5 (-165)
• Moneyline: Cubs -145, Pirates +130
• Total: Over/Under 7.5 (-110/-110)

Run Line, Moneyline and Over/Under

The Cubs are -1.5 favorites versus the Pirates, with +150 at PointsBet the best odds currently available.

For the underdog Pirates (+1.5) to cover the run line, DraftKings Sportsbook has the best odds currently on offer at -165.

Caesars Sportsbook currently has the best moneyline odds for the Cubs at -145, which means you can risk $145 to win $100, for a total payout of $245, if they get the W.

Elsewhere, FanDuel Sportsbook currently has the best moneyline odds for the Pirates at +130, where you can bet $100 to profit $130, earning a total payout of $230, if they win.

The Over/Under is set at 7.5 with Caesars Sportsbook, which currently has the best odds for the Over at -110, as well as the best odds for the Under at -110.

As always, check out the sportsbooks you can bet with in your state for the best MLB odds and lines.

According to DimersBOT, the Pirates (+1.5) are a 64% chance of covering the run line, while the Over/Under total of 7.5 runs is a 54% chance of going Over.

More: Best Bets for Every MLB Game

Best Bets for Pirates vs. Cubs

• Run Line: Pirates +1.5 @ -165 via DraftKings Sportsbook (64% probability)
• Moneyline: Pirates @ +130 via FanDuel Sportsbook (0.2% edge)
• Total: Over 7.5 @ -110 via Caesars Sportsbook (54% probability)

Dimers' best bets are based on world-class simulations and betting intelligence to bring you the best possible plays every time.

While the Cubs are more likely to win the game, according to DimersBOT, betting on the Pirates moneyline is the best option because of the edge found when comparing our data-led probabilities to the sportsbooks' odds currently on offer.

Taking advantage of the edges published here at Dimers is one of the keys to being a profitable bettor in the long run.

Pirates vs. Cubs Probabilities

Use our dynamic widget below to view the latest Moneyline, Over/Under and Run Line probabilities and odds for Pittsburgh vs. CHI Cubs, and click or tap on See Matchup for more.

Dimers has full betting coverage of Tuesday's Pirates-Cubs matchup, including pregame predictions, free betting picks, and live updates.

Don't forget, DimersBOT updates often, so keep an eye on this page for any changes to our betting insights ahead of Pirates vs. Cubs on Tuesday May 17, 2022.

Best Sportsbook Promo for Pirates vs. Cubs

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Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.

Pirates vs. Cubs 2022 Game Info

Tuesday's action between the Cubs and Pirates at Wrigley Field is scheduled to begin at 7:40PM ET.

• Date: Tuesday May 17, 2022
• Time: 7:40PM ET / 4:40PM PT
• Venue: Wrigley Field

Looking to join an online sportsbook and start betting on MLB? Check out the best sportsbook promos in your state.

What other MLB games are on today?

The Pirates and Cubs aren't the only two MLB teams you can bet on. DimersBOT never stops and we've got picks and best bets for each and every MLB game in our MLB Bet Hub page.

Not only do we provide with you top-notch predictions, but we also have recommended bets for the Run Line, Over/Under and Moneyline. Sound good? Check it out now!

Lastly, Dimers' MLB Futures page is our in-house approach to revealing who will win the 2022 World Series, with our data-led probabilities matched against the best odds on the market.