Pirates vs. Cardinals Prediction and Odds - Apr 11, 2022

The St Louis Cardinals and Pittsburgh Pirates clash in the MLB at Busch Stadium on Monday, starting at 2:15PM EDT.

Dakota Hudson (0-0, 0.00 ERA) will get the ball for the Cardinals, while the Pirates are going with Zach Thompson (0-0, 0.00 ERA).

Dimers' best betting picks for Pirates vs. Cardinals, plus game predictions and best odds, are featured below.

Who will win Pirates vs. Cardinals?

Based on high-tech computer power and data, Dimers.com has simulated Monday's Pirates-Cardinals MLB matchup 10,000 times.

Dimers' famous predictive analytics model, DimersBOT, gives the Cardinals a 66% chance of beating the Pirates.

More: Pirates vs. Cardinals Simulated 10,000 Times

Pirates vs. Cardinals Odds

• Run Line: Cardinals -1.5, Pirates +1.5
• Moneyline: Cardinals -185, Pirates +170
• Total: Over/Under 8

Run Line, Moneyline and Over/Under

The Cardinals are -1.5 favorites versus the Pirates, with +112 at FanDuel Sportsbook the best odds currently available.

For the underdog Pirates (+1.5) to cover the run line, DraftKings Sportsbook has the best odds currently on offer at -125.

BetMGM currently has the best moneyline odds for the Cardinals at -185, which means you can risk $185 to win $100, for a total payout of $285, if they get the W.

Elsewhere, DraftKings Sportsbook currently has the best moneyline odds for the Pirates at +170, where you can bet $100 to profit $170, earning a total payout of $270, if they win.

The Over/Under for total runs scored is set at 8 with DraftKings Sportsbook, which currently has the best odds for the Over at -115, while PointsBet currently has the best odds for the Under at -110.

As always, check out all the legal sportbooks available in your state for the best MLB odds and lines.

According to DimersBOT, the Pirates (+1.5) are a 54% chance of covering the run line, while the Over/Under total of 8 runs is a 54% chance of going Over.

More: Predictions for Every MLB Matchup

Best Bets for Pirates vs. Cardinals

• Run Line: Cardinals -1.5 @ +112 via FanDuel Sportsbook
• Moneyline: Cardinals @ -185 via BetMGM (66% probability)
• Total: Over 8 @ -115 via DraftKings Sportsbook (54% probability)

Dimers' best bets are based on detailed simulations and wagering intelligence to help you make more informed decisions with the legal sportsbooks in the United States.

Even though the Pirates are more likely to cover the run line, our best bet of Cardinals -1.5 is based on the chance of that happening, according to DimersBOT, and the top odds available.

Pirates vs. Cardinals Probabilities

Use our dynamic widget below to explore up-to-date Moneyline, Over/Under and Run Line probabilities and odds for Pittsburgh vs. St Louis, and click or tap on See Matchup to reveal more.

Dimers has full betting coverage of Monday's Pirates-Cardinals matchup, including pre-game predictions, top betting picks, and live win probabilities.

Remember, DimersBOT updates frequently, so keep checking this page for any changes to our betting insights ahead of Pirates vs. Cardinals on Monday April 11, 2022.

Risk-Free Bet for Pirates vs. Cardinals

Looking for the best sportsbook offer in America for Pittsburgh vs. St Louis? Join FanDuel Sportsbook today and get your first bet risk free up to $1,000, which you can use on Monday's Pirates-Cardinals matchup.

All you need to do is click or tap on this exclusive FanDuel Sportsbook link and create a new account – it's easy and takes less than 2 minutes.

Then, make your first deposit and place a bet up to $1,000 on Pirates vs. Cardinals. If you don't win your bet, FanDuel Sportsbook will refund it in site credit!

This offer is available to all new FanDuel Sportsbook users. How good is that!

Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.

Pirates vs. Cardinals 2022 Game Info

When do the Cardinals play the Pirates?

• Date: Monday April 11, 2022
• Time: 2:15PM EDT / 11:15AM PDT
• Venue: Busch Stadium

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What MLB games are on today?

Now you've got the 411 on Pirates vs. Cardinals, take a look at the latest betting predictions for all upcoming MLB games in Dimers' MLB Bet Hub, where you can find probabilities and odds, and our best bets for each and every MLB matchup.

Want a pick for the Run Line? You got it. How about the Over/Under? Yup, got that too. The Moneyline? Yes sir. And these picks are good, I mean REALLY good. Take a look now!

Finally, Dimers' Baseball Futures page is our in-house approach to determining who will win the 2022 World Series, with our data-led probabilities matched against the best odds to win the World Series.