Pirates vs. Cardinals Prediction and Odds - Apr 10, 2022

MLB action continues on Sunday at 2:15PM EDT as the Pittsburgh Pirates take on the St Louis Cardinals at Busch Stadium.

Steven Matz (0-0, 0.00 ERA) will get the ball for the Cardinals, while the Pirates are going with Bryse Wilson (0-0, 0.00 ERA).

Dimers' free betting picks for Pirates vs. Cardinals, plus game predictions and best odds, are featured below.

Who will win Pirates vs. Cardinals?

Using trusted machine learning and data, Dimers.com has simulated Sunday's Pirates-Cardinals MLB game 10,000 times.

Dimers' independent predictive analytics model, DimersBOT, gives the Cardinals a 69% chance of defeating the Pirates.

MORE: Pirates vs. Cardinals Simulated 10K Times

Run Line, Moneyline and Over/Under

The Cardinals are -1.5 favorites against the Pirates, with -105 at BetMGM the best odds currently available.

For the underdog Pirates (+1.5) to cover the run line, DraftKings Sportsbook has the best odds currently on offer at -110.

BetMGM currently has the best moneyline odds for the Cardinals at -200, which means you can risk $200 to win $100, for a total payout of $300, if they get the W.

Meanwhile, FanDuel Sportsbook currently has the best moneyline odds for the Pirates at +194, where you can put down $100 to profit $194, earning a total payout of $294, if they win.

The Over/Under for total runs scored sits at 8.5 with PointsBet, which currently has the best odds for the Over at +100, while FanDuel Sportsbook currently has the best odds for the Under at -106.

As always, make sure you check all the sportsbooks that are available in your state for the best MLB odds and lines.

According to DimersBOT, the Pirates (+1.5) are a 52% chance of covering the run line, while the Over/Under total of 8.5 runs is a 51% chance of going Under.

MORE: Live Scores for All Major Sports

Best Bets for Pirates vs. Cardinals

• Run Line: Pirates +1.5 @ -110 via DraftKings Sportsbook (52% probability)
• Moneyline: Cardinals @ -200 via BetMGM (69% probability)
• Over/Under: Under 8.5 @ -106 via FanDuel Sportsbook (51% probability)

Dimers' best bets are based on complex simulations and wagering intelligence to bring you the best possible plays 24/7/365.

Pirates vs. Cardinals Probabilities

Use our dynamic widget below to explore the latest Moneyline, Over/Under and Run Line probabilities and odds for Pittsburgh vs. St Louis, and click or tap on See Matchup for more.

Dimers has full betting coverage of Sunday's Pirates-Cardinals matchup, including pre-game predictions, top betting picks, and live scores.

Don't forget, DimersBOT updates often, so check this page for the latest betting analysis ahead of Pirates vs. Cardinals on Sunday April 10, 2022.

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Pirates vs. Cardinals 2022 Game Info

When do the Cardinals play the Pirates?

• Date: Sunday April 10, 2022
• Time: 2:15PM EDT / 11:15AM PDT
• Venue: Busch Stadium

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What MLB games are on today?

Now you've got the 411 on Pirates vs. Cardinals, get the latest betting analysis for all upcoming MLB games in Dimers' MLB Bet Hub, where you can find probabilities and odds, as well as our best bets for each and every MLB matchup.

Want a pick for the Run Line? You got it. How about the Over/Under? Yup, got that too. The Moneyline? Yes sir. And these picks are good, I mean REALLY good. Take a look now!