Pirates vs. Brewers Prediction and Odds - Apr 20, 2022

The Milwaukee Brewers take on the Pittsburgh Pirates in MLB action at American Family Field on Wednesday, starting at 1:40PM EDT.

The Brewers will send Brandon Woodruff (1-1, 7.27 ERA) to the mound, while the Pirates will counter with Mitch Keller (0-2, 9.39 ERA).

Dimers' free betting picks for Pirates vs. Brewers, plus game predictions and best odds, are detailed in this article.

Who will win Pirates vs. Brewers?

Using trusted computer power and data, Dimers.com has simulated Wednesday's Pirates-Brewers MLB game 10,000 times.

Dimers' renowned predictive analytics model, DimersBOT, gives the Brewers a 65% chance of defeating the Pirates.

More: Pirates vs. Brewers Simulated 10,000 Times

Pirates vs. Brewers Odds

• Run Line: Brewers -1.5 (-120), Pirates +1.5 (+108)
• Moneyline: Brewers -250, Pirates +210
• Total: Over/Under 8 (-105/-105)

Run Line, Moneyline and Over/Under

The Brewers are -1.5 favorites against the Pirates, with -120 at BetMGM the best odds currently available.

For the underdog Pirates (+1.5) to cover the run line, FanDuel Sportsbook has the best odds currently on offer at +108.

BetMGM currently has the best moneyline odds for the Brewers at -250, which means you can risk $250 to win $100, for a total payout of $350, if they get the W.

Meanwhile, FanDuel Sportsbook currently has the best moneyline odds for the Pirates at +210, where you can bet $100 to profit $210, earning a total payout of $310, if they win.

The Over/Under for total runs scored is set at 8 with FanDuel Sportsbook, which currently has the best odds for the Over at -105, while BetMGM currently has the best odds for the Under at -105.

As always, check out the sportsbooks you have access to in your state for the best MLB odds and lines.

According to DimersBOT, the Pirates (+1.5) are a 52% chance of covering the run line, while the Over/Under total of 8 runs is considered an equal 50-50 chance of hitting.

More: Live Scores for All Major Sports

Best Bets for Pirates vs. Brewers

• Run Line: Pirates +1.5 @ +108 via FanDuel Sportsbook (52% probability) 🔥
• Moneyline: Pirates @ +210 via FanDuel Sportsbook (2.7% edge)
• Total: Over 8 @ -105 via FanDuel Sportsbook (50% probability)

Any time you see a 🔥, that means it's one of Dimers' best bets of the day across any sport.

Dimers' best bets are based on complex simulations and wagering intelligence to help you make smarter decisions with the legal sportsbooks in the United States.

While the Brewers are more likely to win the game, according to DimersBOT, taking the Pirates moneyline is the best option because of the 2.7% edge found when comparing our data-led probabilities to the betting odds currently available.

Taking advantage of the edges seen on Dimers is pivotal to achieving long-term profitability as a sports bettor.

Pirates vs. Brewers Betting Guide

Use our interactive widget below to explore the latest Moneyline, Over/Under and Run Line probabilities and odds for Pittsburgh vs. Milwaukee, and click or tap on See Matchup to reveal more.

Dimers has full betting coverage of Wednesday's Pirates-Brewers matchup, including pre-game predictions, computer picks, and live win probabilities.

Remember, DimersBOT updates frequently, so check this page for the latest betting analysis before Pirates vs. Brewers on Wednesday April 20, 2022.

Best Betting Offer for Pirates vs. Brewers

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Simply click or tap on this exclusive FanDuel Sportsbook link and create a new account – it's easy and takes less than 2 minutes.

Then, make your first deposit and place a bet up to $1,000 on Pirates vs. Brewers. If your bet doesn't win, FanDuel Sportsbook will give it back to you in site credit!

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Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.

Pirates vs. Brewers 2022 Game Info

When do the Brewers play the Pirates?

• Date: Wednesday April 20, 2022
• Time: 1:40PM EDT / 10:40AM PDT
• Venue: American Family Field

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Want more MLB analysis like this?

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We use the power of predictive analytics to find value in the markets so we can produce the best MLB betting previews available. We do this by comparing our own probabilities against the sportsbooks' odds (aka Vegas odds) as soon as they go live.

So, get ahead of the game and beat the 'books today – it's only a click away.

While you're here, Dimers' Baseball Futures page is our in-house approach to revealing who will win the 2022 World Series, with our data-led probabilities compared to the best odds on the market.