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Pennsylvania vs. Villanova prediction: Villanova favored to win men's college basketball matchup [12/6/2025]
Updated: | First published:
Written by Dave Garofolo, Content Producer
Get Pennsylvania vs Villanova predictions for college basketball Saturday.
Villanova and Pennsylvania will lock horns in men's college basketball action at Xfinity Mobile Arena on Saturday, starting at 7:30PM ET.
Based on the latest simulation results, Dimers' advanced college basketball model projects Villanova as the most likely winner of the Pennsylvania vs. Villanova game.
This article offers further insights into Saturday's matchup, including an expanded look at the predicted score, best bets and picks.
Pennsylvania vs. Villanova prediction: Who will win and cover?
Using trusted machine learning and data, we have simulated the outcome of Saturday's NCAA basketball matchup between Pennsylvania and Villanova 10,000 times as part of our men's college basketball predictions coverage.
Our leading predictive model currently gives Villanova a 96% chance of beating Pennsylvania. Our predicted final score has Villanova winning 83-63.
According to our model, the bookmakers have got it right, and Pennsylvania and Villanova each have a 50% chance of covering the spread, while the 148.5-point over/under has a 52% chance of staying under.
Pennsylvania vs. Villanova odds
We have researched the best men's college basketball odds in America for this game, which are listed here:
| Bet Type | Pennsylvania | Villanova |
|---|---|---|
| Spread | +19.5 (-110) | -19.5 (-105) |
| Moneyline | +1400 | -3000 |
| Total | o148.5 (-110) | u148.5 (-105) |
All odds are correct at the time of publication and are subject to change.
Pennsylvania vs. Villanova picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Villanova -19.5 | -105 |
| Moneyline | Villanova | -3000 |
| Total | Under 148.5 | -105 |
According to our best men's college basketball bets, the top play to make on this game is Under 148.5 total points.
Pennsylvania vs. Villanova game-day updates and essential details
Saturday's men's college basketball matchup between Villanova and Pennsylvania at Xfinity Mobile Arena is scheduled to start at 7:30PM ET.
- Who: Pennsylvania vs. Villanova
- Date: Saturday, December 6, 2025
- Time: 7:30PM ET/4:30PM PT
- Venue: Xfinity Mobile Arena
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Conclusion
We predict Villanova, with a 96% win probability, will likely beat Pennsylvania on Saturday.
AI and automation have enhanced this article to quickly deliver accurate Pennsylvania vs. Villanova insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
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