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Penn State vs. Pittsburgh prediction: Why Penn State is favored to win men's college basketball matchup [12/21/2025]
Updated: | First published:
Written by Jason Bevilacqua, Head of Content and Communities
Get Penn State vs Pittsburgh predictions for college basketball Sunday.
Pittsburgh will face Penn State, in what is expected to be a close Men's College Basketball game, at GIANT Center on Sunday, starting at 12:00 PM ET.
Based on updated simulation results, Dimers' advanced college basketball model gives Penn State a slight edge with a 52% win probability over Pittsburgh.
This article offers an expanded analysis of Sunday's Penn State vs. Pittsburgh matchup, including an expanded look at the predicted score, best bets and picks.
Penn State vs. Pittsburgh prediction: Who will win and cover?
Using innovative machine learning and data analysis, we have simulated the result of Sunday's NCAA basketball matchup between Penn State and Pittsburgh 10,000 times as part of our men's college basketball predictions coverage.
Our famous predictive model gives Penn State a 52% chance of defeating Pittsburgh. Our predicted final score has Penn State winning 73-72.
According to our model, Penn State (+1.5) has a 55% chance of covering the spread, while the over/under total of 146.5 points has a 55% chance of staying under.
Penn State vs. Pittsburgh odds
We have researched the best men's college basketball odds in America for this game, which are listed here:
| Bet Type | Penn State | Pittsburgh |
|---|---|---|
| Spread | +1.5 (-122) | -1.5 (+102) |
| Moneyline | -105 | -105 |
| Total | o146.5 (-110) | u146.5 (-105) |
All odds are correct at the time of publication and are subject to change.
Penn State vs. Pittsburgh picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Penn State +1.5 | -122 |
| Moneyline | Penn State | -105 |
| Total | Under 146.5 | -105 |
According to our men's college basketball best bets, the top play to make on this game is Under 146.5 total points.
Penn State vs. Pittsburgh game-day updates and essential details
Sunday's men's college basketball action between Pittsburgh and Penn State at GIANT Center is scheduled to commence at 12:00 PM ET.
- Who: Penn State vs. Pittsburgh
- Date: Sunday, December 21, 2025
- Time: 12:00 PM ET/9:00AM PT
- Venue: GIANT Center
Conclusion
We predict Penn State, with a 52% win probability, will likely beat Pittsburgh on Sunday.
AI and automation have enhanced this article to quickly deliver accurate Penn State vs. Pittsburgh insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.
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