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Penn State vs. Pittsburgh prediction: Why Pittsburgh is favored to win men's college basketball matchup [12/21/2025]
Updated: | First published:
Written by Jason Bevilacqua, Head of Content and Communities
Get Penn State vs Pittsburgh predictions for college basketball Sunday.
Pittsburgh and Penn State are scheduled to meet in men's college basketball action at GIANT Center on Sunday, with tipoff at 12:00 PM ET.
Based on updated simulations, Dimers' advanced college basketball model gives Pittsburgh a slight edge with a 52% win probability over Penn State.
This article offers a closer look at Sunday's Penn State vs. Pittsburgh matchup, including an expanded look at the predicted score, best bets and picks.
Penn State vs. Pittsburgh prediction: Who will win and cover?
Using trusted machine learning and data, we have simulated the outcome of Sunday's NCAA basketball game between Penn State and Pittsburgh 10,000 times as part of our men's college basketball predictions coverage.
Our independent predictive model currently gives Pittsburgh a 52% chance of beating Penn State. Our predicted final score has Pittsburgh winning 73-72.
According to our model, Pittsburgh (+1.5) has a 54% chance of covering the spread, while the over/under total of 146.5 points has a 54% chance of staying under.
Penn State vs. Pittsburgh odds
We have researched the best men's college basketball odds in America for this game, which are listed here:
| Bet Type | Penn State | Pittsburgh |
|---|---|---|
| Spread | -1.5 (+105) | +1.5 (-118) |
| Moneyline | -110 | -108 |
| Total | o146.5 (-105) | u146.5 (-110) |
All odds are correct at the time of publication and are subject to change.
Penn State vs. Pittsburgh picks and best bet
After matching our probabilities against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Pittsburgh +1.5 | -118 |
| Moneyline | Pittsburgh | -108 |
| Total | Under 146.5 | -110 |
According to our men's college basketball best bets, the top play to make on this game is Under 146.5 total points.
Penn State vs. Pittsburgh game-day updates and essential details
Sunday's men's college basketball action between Pittsburgh and Penn State at GIANT Center is scheduled to start at 12:00 PM ET.
- Who: Penn State vs. Pittsburgh
- Date: Sunday, December 21, 2025
- Time: 12:00 PM ET/9:00AM PT
- Venue: GIANT Center
Conclusion
We predict Pittsburgh, with a 52% win probability, will likely beat Penn State on Sunday.
AI and automation have enhanced this article to quickly deliver accurate Penn State vs. Pittsburgh insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.
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