Padres vs. Pirates Prediction and Odds - Apr 29, 2022

MLB action continues on Friday at 6:35PM ET as the San Diego Padres lock horns with the Pittsburgh Pirates at PNC Park.

Zach Thompson (0-2, 10.80 ERA) will get the ball for the Pirates, pitting him against Yu Darvish (1-1, 4.43 ERA) for the Padres.

Dimers' best betting picks for Padres vs. Pirates, as well as game predictions and best odds, are featured in this article.

Who will win Padres vs. Pirates?

Using advanced machine learning and data, Dimers.com has simulated Friday's Padres-Pirates MLB matchup 10,000 times.

Dimers' popular predictive analytics model, DimersBOT, currently gives the Padres a 63% chance of beating the Pirates.

More: Padres vs. Pirates Simulated 10,000 Times

Padres vs. Pirates Current Odds

• Run Line: Pirates +1.5 (-110), Padres -1.5 (+100)
• Moneyline: Pirates +160, Padres -175
• Total: Over/Under 7.5 (+100/-120)

Run Line, Moneyline and Over/Under

The Pirates are currently +1.5 underdogs versus the Padres, with -110 at DraftKings Sportsbook the best odds currently available.

For the favored Padres (-1.5) to cover the run line, FanDuel Sportsbook has the best odds currently on offer at +100.

DraftKings Sportsbook currently has the best moneyline odds for the Pirates at +160. That means you can bet $100 to profit $160, earning a total payout of $260, if they win.

On the other hand, BetMGM currently has the best moneyline odds for the Padres at -175, where you can risk $175 to win $100, for a total payout of $275, if they come out on top.

The Over/Under for total runs scored sits at 7.5 with BetMGM, which currently has the best odds for the Over at +100, as well as the best odds for the Under at -120.

As always, check out all the sportsbooks available in your state for the best MLB odds and lines.

According to DimersBOT, the Pirates (+1.5) are a 52% chance of covering the run line, while the 7.5-run Over/Under is a 54% chance of going Over.

More: Best Bets for Every MLB Game

Best Bets for Padres vs. Pirates

• Run Line: Pirates +1.5 @ -110 via DraftKings Sportsbook (52% probability)
• Moneyline: Padres @ -175 via BetMGM (63% probability)
• Total: Over 7.5 @ +100 via BetMGM (54% probability) 🔥

When you see a 🔥, that means it's one of Dimers' best free picks today across all major pro and college sports.

Dimers' best bets are based on world-class simulations and betting intelligence to serve you the best possible plays every day of the year.

Padres vs. Pirates Betting Guide

Use our dynamic widget below to explore the latest Moneyline, Over/Under and Run Line probabilities and odds for San Diego vs. Pittsburgh, and click or tap on See Matchup to reveal more.

Dimers has full betting coverage of Friday's Padres-Pirates matchup, including pregame predictions, free betting picks, and live win probabilities.

Don't forget, DimersBOT updates regularly, so refresh this page for the latest betting analysis ahead of Padres vs. Pirates on Friday April 29, 2022.

Get a Risk-Free Bet for Padres vs. Pirates

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Simply click or tap on this exclusive FanDuel Sportsbook link and create an account – it's easy and takes less than 2 minutes.

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Padres vs. Pirates 2022 Game Info

When do the Pirates play the Padres?

• Date: Friday April 29, 2022
• Time: 6:35PM ET / 3:35PM PT
• Venue: PNC Park

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