Padres vs. Giants Prediction and Odds - Apr 12, 2022

MLB action continues on Tuesday at 9:45PM EDT as the San Diego Padres lock horns with the San Francisco Giants at Oracle Park.

The Giants will have Alex Cobb (0-0, 0.00 ERA) start, pitting him against Yu Darvish (0-0, 0.00 ERA) for the Padres.

Dimers' top betting picks for Padres vs. Giants, plus game predictions and best odds, are featured below.

Who will win Padres vs. Giants?

Using advanced computer power and data, Dimers.com has simulated Tuesday's Padres-Giants MLB game 10,000 times.

Dimers' popular predictive analytics model, DimersBOT, gives the Giants a 52% chance of winning against the Padres.

More: Free Betting Analysis for Padres vs. Giants

Padres vs. Giants Current Odds

• Run Line: Giants +1.5, Padres -1.5
• Moneyline: Giants -115, Padres +105
• Total: Over/Under 7.5

Run Line, Moneyline and Over/Under

The Giants are +1.5 underdogs against the Padres, with -169 at Caesars Sportsbook the best odds currently available.

For the favored Padres (-1.5) to cover the run line, DraftKings Sportsbook has the best odds currently on offer at +165.

Caesars Sportsbook currently has the best moneyline odds for the Giants at -115, which means you can risk $115 to win $100, for a total payout of $215, if they get the W.

Meanwhile, DraftKings Sportsbook currently has the best moneyline odds for the Padres at +105, where you can bet $100 to profit $105, earning a total payout of $205, if they win.

The Over/Under is set at 7.5 with PointsBet, which currently has the best odds for the Over at -110, while Caesars Sportsbook currently has the best odds for the Under at -105.

As always, make sure you check the sportsbooks you have access to in your state for the best MLB odds and lines.

According to DimersBOT, the Giants (+1.5) are a 54% chance of covering the run line, while the Over/Under total of 7.5 runs is a 53% chance of going Over.

More: Live Scores for All Major Sports

Best Bets for Padres vs. Giants

• Run Line: Padres -1.5 @ +165 via DraftKings Sportsbook (8.6% edge) 🔥
• Moneyline: Padres @ +105 via DraftKings Sportsbook
• Total: Over 7.5 @ -110 via PointsBet (53% probability)

When you see a 🔥, that means it's one of our best bets today across all sports.

Dimers' best bets are based on complex simulations and wagering intelligence to bring you the best possible plays 24/7/365.

Even though the Giants are more likely to cover the run line, our best bet of Padres -1.5 is based on the expectation of that happening, according to DimersBOT, and the best odds available.

And while the Giants are more likely to win the game, according to DimersBOT, betting on the Padres moneyline is the best option due to the edge found when comparing our data-led probabilities to the betting odds currently on offer.

Taking advantage of the edges seen here at Dimers is crucial to being a profitable bettor in the long run.

Padres vs. Giants Probabilities

Use our widget below to see up-to-date Moneyline, Over/Under and Run Line probabilities and odds for San Diego vs. San Francisco, and click or tap on See Matchup for more.

Dimers has full coverage of Tuesday's Padres-Giants matchup, including pre-game predictions, top betting picks, and live win probabilities.

Don't forget, DimersBOT updates often, so refresh this article for any changes to our betting analysis before Padres vs. Giants on Tuesday April 12, 2022.

Risk-Free Bet for Padres vs. Giants

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Simply click or tap on this exclusive FanDuel Sportsbook link and create a new account – it's easy and takes less than 2 minutes.

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Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.

Padres vs. Giants 2022 Game Info

When do the Giants play the Padres?

• Date: Tuesday April 12, 2022
• Time: 9:45PM EDT / 6:45PM PDT
• Venue: Oracle Park

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What other MLB games are on today?

Now you've got the 411 on Padres vs. Giants, get the latest betting predictions for all upcoming MLB games in our MLB Bet Hub. There you can find probabilities and odds, plus our best bets for each and every MLB matchup.

Want a pick for the Run Line? You got it. How about the Over/Under? Yup, got that too. The Moneyline? Yes sir. And these picks are good, I mean REALLY good. Take a look now!

Lastly, Dimers' Baseball Futures page is our in-house approach to determining who will win the 2022 World Series, with our data-led probabilities compared to the best odds to win the World Series.