Padres vs. D-Backs Prediction and Odds - Apr 8, 2022

The Arizona D-Backs and San Diego Padres are scheduled to meet in the MLB at Chase Field on Friday, starting at 9:40PM EDT.

Merrill Kelly (0-0, 0.00 ERA) will be on the bump for the D-Backs, while the Padres will counter with Sean Manaea (0-0, 0.00 ERA).

Dimers' best betting picks for Padres vs. D-Backs, plus game predictions and best odds, are featured in this article.

Who will win Padres vs. D-Backs?

Using state-of-the-art machine learning and data, Dimers.com has simulated Friday's Padres-D-Backs MLB matchup 10,000 times.

Dimers' revolutionary predictive analytics model, DimersBOT, gives the Padres a 58% chance of defeating the D-Backs.

MORE: Padres vs. D-Backs Simulated 10,000 Times

Run Line, Moneyline and Over/Under

The D-Backs are +1.5 underdogs versus the Padres, with -130 at Caesars Sportsbook the best odds currently available.

For the favored Padres (-1.5) to cover the run line, PointsBet has the best odds currently on the market at +115.

BetMGM currently has the best moneyline odds for the D-Backs at +125, which means you can bet $100 to profit $125, earning a total payout of $225, if they win.

Elsewhere, PointsBet currently has the best moneyline odds for the Padres at -140, where you can risk $140 to win $100, for a total payout of $240, if they come out on top.

The Over/Under for total runs scored sits at 8.5 with DraftKings Sportsbook, which currently has the best odds for the Over at -115, while FanDuel Sportsbook currently has the best odds for the Under at +100.

As always, make sure you check the sportsbooks you have access to in your state for the best MLB odds and lines.

According to DimersBOT, the D-Backs (+1.5) are a 56% chance of covering the run line, while the 8.5-run Over/Under is a 57% chance of going Over.

MORE: Predictions for Every MLB Matchup

Best Bets for Padres vs. D-Backs

• Run Line: D-Backs +1.5 @ -130 via Caesars Sportsbook (56% probability)
• Moneyline: Padres @ -140 via PointsBet (58% probability)
• Over/Under: Over 8.5 @ -115 via DraftKings Sportsbook (57% probability)

Dimers' best bets are based on world-class simulations and wagering intelligence to help you make more informed investments with the legal sportsbooks in the USA.

Padres vs. D-Backs Probabilities

Use our dynamic widget below to view up-to-date Moneyline, Over/Under and Run Line probabilities and odds for San Diego vs. Arizona, and click or tap on See Matchup to reveal more.

Dimers has full betting coverage of Friday's Padres-D-Backs matchup, including pre-game predictions, free betting picks, and live scores.

Remember, DimersBOT updates regularly, so refresh this article for any changes to our betting insights before Padres vs. D-Backs on Friday April 8, 2022.

Risk-Free Bet for Padres vs. D-Backs

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Padres vs. D-Backs 2022 Game Info

When do the D-Backs play the Padres?

• Date: Friday April 8, 2022
• Time: 9:40PM EDT / 6:40PM PDT
• Venue: Chase Field

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