Orioles vs. Yankees Prediction and Odds - Apr 26, 2022

The New York Yankees square off with the Baltimore Orioles in MLB action at Yankee Stadium on Tuesday, starting at 7:05PM ET.

Luis Severino (1-0, 2.08 ERA) will start for the Yankees, while the Orioles are going with Jordan Lyles (1-1, 3.52 ERA).

Dimers' top betting picks for Orioles vs. Yankees, plus game predictions and best odds, are featured in this article.

Who will win Orioles vs. Yankees?

Based on trusted computer power and data, Dimers.com has simulated Tuesday's Orioles-Yankees MLB game 10,000 times.

Dimers' famous predictive analytics model, DimersBOT, currently gives the Yankees a 70% chance of getting the W against the Orioles.

More: Orioles vs. Yankees Simulated 10,000 Times

Orioles vs. Yankees Odds

• Run Line: Yankees -1.5 (-130), Orioles +1.5 (+125)
• Moneyline: Yankees -275, Orioles +240
• Total: Over/Under 7.5 (-110/+100)

Run Line, Moneyline and Over/Under

The Yankees are -1.5 favorites against the Orioles, with -130 at DraftKings Sportsbook the best odds currently available.

For the underdog Orioles (+1.5) to cover the run line, FanDuel Sportsbook has the best odds currently on the market at +125.

BetMGM currently has the best moneyline odds for the Yankees at -275, which means you can risk $275 to win $100, for a total payout of $375, if they get the W.

On the other hand, FanDuel Sportsbook currently has the best moneyline odds for the Orioles at +240, where you can bet $100 to profit $240, earning a total payout of $340, if they win.

The Over/Under sits at 7.5 with DraftKings Sportsbook, which currently has the best odds for the Over at -110, while BetMGM currently has the best odds for the Under at +100.

As always, check out the sportsbooks you have access to in your state for the best MLB odds and lines.

According to DimersBOT, the Yankees (-1.5) are a 51% chance of covering the run line, while the 7.5-run Over/Under is a 59% chance of going Over.

More: Today's Best Bets for All Major Sports

Best Bets for Orioles vs. Yankees

• Run Line: Orioles +1.5 @ +125 via FanDuel Sportsbook (4.8% edge) 🔥
• Moneyline: Orioles @ +240 via FanDuel Sportsbook (1.0% edge)
• Total: Over 7.5 @ -110 via DraftKings Sportsbook (59% probability) 🔥

When you see a 🔥, that means it's one of our best bets today across all major pro and college sports.

Dimers' best bets are based on world-class simulations and betting intelligence to help you make more informed decisions with the legal sportsbooks in America.

Although the Yankees are more likely to cover the run line, our best bet of Orioles +1.5 is based on the chance of that happening, according to DimersBOT, and the best odds available.

And while the Yankees are more likely to win the game, according to DimersBOT, taking the Orioles moneyline is the best option due to the 1.0% edge identified when comparing our data-led probabilities to the sportsbooks' odds currently available.

Taking advantage of the edges seen on Dimers.com is one of the keys to being profitable in the long run.

Orioles vs. Yankees Betting Guide

Use our dynamic widget below to see the latest Moneyline, Over/Under and Run Line probabilities and odds for Baltimore vs. NY Yankees, and click or tap on See Matchup for more.

Dimers has full betting coverage of Tuesday's Orioles-Yankees matchup, including pregame predictions, free picks, and live updates.

Remember, DimersBOT updates often, so refresh this page for any changes to our betting insights ahead of Orioles vs. Yankees on Tuesday April 26, 2022.

Best Sportsbook Promo for Orioles vs. Yankees

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Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.

Orioles vs. Yankees 2022 Game Info

When do the Yankees play the Orioles?

• Date: Tuesday April 26, 2022
• Time: 7:05PM ET / 4:05PM PT
• Venue: Yankee Stadium

Looking to join an online sportsbook and start betting on MLB today? We've reviewed the best available sign-up offers for each legal betting state.

What MLB games are on today?

Now you've got the 411 on Orioles vs. Yankees, get the latest betting coverage for all upcoming MLB games in Dimers' MLB Bet Hub. There you can find probabilities and odds, and our best bets for each and every MLB matchup.

Want a pick for the Run Line? You got it. How about the Over/Under? Yup, got that too. The Moneyline? Yes sir. And these picks are good, I mean REALLY good. Take a look now!

Lastly, Dimers' Baseball Futures page is our in-house approach to revealing who will win the 2022 World Series, with our data-led probabilities paired with the best odds to win the World Series.