Orioles vs. White Sox Prediction and Odds - Jun 26, 2022

The Chicago White Sox and Baltimore Orioles lock horns in MLB at Guaranteed Rate Field on Sunday, starting at 2:10PM ET.

Dylan Cease (5-3, 2.68 ERA) will start for the White Sox, up against Jordan Lyles (4-6, 4.92 ERA) for the Orioles.

Dimers' free betting picks for Orioles vs. White Sox, plus game predictions and best odds, are detailed below.

Who will win Orioles vs. White Sox?

Using state-of-the-art machine learning and data, Dimers.com has simulated Sunday's Orioles-White Sox MLB game 10,000 times.

Dimers' independent predictive analytics model, DimersBOT, currently gives the White Sox a 67% chance of getting the W against the Orioles.

More: Orioles vs. White Sox Simulated 10K Times

Orioles vs. White Sox Odds

• Run Line: White Sox -1.5 (-110), Orioles +1.5 (+100)
• Moneyline: White Sox -225, Orioles +195
• Total: Over/Under 9 (+105/-114)

Run Line, Moneyline and Over/Under

The White Sox are listed as -1.5 favorites versus the Orioles, with -110 at BetMGM the best odds currently available.

For the underdog Orioles (+1.5) to cover the run line, DraftKings Sportsbook has the best odds currently on the market at +100.

BetMGM currently has the best moneyline odds for the White Sox at -225. That means you can risk $225 to win $100, for a total payout of $325, if they get the W.

Elsewhere, Caesars Sportsbook currently has the best moneyline odds for the Orioles at +195, where you can put down $100 to profit $195, earning a total payout of $295, if they win.

The Over/Under is set at 9 with PointsBet, which currently has the best odds for the Over at +105, while FanDuel Sportsbook currently has the best odds for the Under at -114.

As always, check out all the legal sportbooks that are available in your state for the best MLB odds and lines.

According to DimersBOT, the Orioles (+1.5) are a 51% chance of covering the run line, while the 9-run Over/Under is a 51% chance of going Under.

More: Best Bets for Every MLB Game

Best Bets for Orioles vs. White Sox

• Run Line: Orioles +1.5 @ +100 via DraftKings Sportsbook (51% probability)
• Moneyline: Orioles @ +195 via Caesars Sportsbook
• Total: Over 9 @ +105 via PointsBet (0.1% edge)

Our best bets are based on detailed modeling and gambling expertise to help you make smarter investments with your state's legal sportsbooks.

While the White Sox are more likely to win the game, according to DimersBOT, betting on the Orioles moneyline is the best option because of the edge found when comparing our data-led probabilities to the sportsbooks' odds currently on offer.

Taking advantage of the edges published on Dimers is pivotal to achieving long-term profitability.

Furthermore, despite the Under being more likely to hit on this occasion, Over 9 is our best bet on account of the better odds (+105) that are available from PointsBet.

Orioles vs. White Sox Prediction

Use our interactive widget below to view the latest Moneyline, Over/Under and Run Line probabilities and odds for Baltimore vs. CHI White Sox, and click or tap on See Matchup for more.

Dimers has full coverage of Sunday's Orioles-White Sox matchup, including pregame predictions, computer picks, and live win probabilities.

Don't forget, DimersBOT updates regularly, so keep checking this page for any changes to our betting analysis before Orioles vs. White Sox on Sunday June 26, 2022.

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Orioles vs. White Sox 2022 Game Info

Sunday's action between the White Sox and Orioles at Guaranteed Rate Field is scheduled to commence at 2:10PM ET.

• Who: Chicago White Sox vs. Baltimore Orioles
• Date: Sunday June 26, 2022
• Time: 2:10PM ET / 11:10AM PT
• Venue: Guaranteed Rate Field

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What other MLB games are on today?

Now you've got the 411 on Orioles vs. White Sox, take a look at the latest betting coverage for all upcoming MLB games in our MLB Bet Hub. There you can find probabilities and odds, and our best bets for each and every MLB matchup.

Want a pick for the Run Line? You got it. How about the Over/Under? Yup, got that too. The Moneyline? Yes sir. And these picks are good, I mean REALLY good. Take a look now!

While you're here, Dimers' Baseball Futures page is our in-house approach to determining who will win the 2022 World Series, with our data-led probabilities matched against the best odds available.