Orioles vs. Cardinals Prediction and Odds - May 12, 2022

The St Louis Cardinals square off with the Baltimore Orioles in MLB action at Busch Stadium on Thursday, beginning at 1:15PM ET.

Steven Matz (3-2, 7.01 ERA) will be on the bump for the Cardinals, while the Orioles are going with Bryan Baker (1-1, 5.40 ERA).

Dimers' best betting picks for Orioles vs. Cardinals, as well as game predictions and best odds, are featured below.

Today's Baltimore vs. St Louis betting preview is brought to you by PointsBet, which has a tasty 5x $100 Risk-Free Bets offer for new users.

Who will win Orioles vs. Cardinals?

Using state-of-the-art machine learning and data, Dimers.com has simulated Thursday's Orioles-Cardinals MLB matchup 10,000 times.

Dimers' leading predictive analytics model, DimersBOT, gives the Cardinals a 65% chance of getting the W against the Orioles.

More: Free Betting Analysis for Orioles vs. Cardinals

Orioles vs. Cardinals Odds

• Run Line: Cardinals -1.5 (+105), Orioles +1.5 (-118)
• Moneyline: Cardinals -200, Orioles +184
• Total: Over/Under 8.5 (-105/-110)

Run Line, Moneyline and Over/Under

The Cardinals are -1.5 favorites versus the Orioles, with +105 at Caesars Sportsbook the best odds currently available.

For the underdog Orioles (+1.5) to cover the run line, FanDuel Sportsbook has the best odds currently on offer at -118.

BetMGM currently has the best moneyline odds for the Cardinals at -200, which means you can risk $200 to win $100, for a total payout of $300, if they get the W.

On the other hand, FanDuel Sportsbook currently has the best moneyline odds for the Orioles at +184, where you can bet $100 to profit $184, earning a total payout of $284, if they win.

The Over/Under for total runs scored sits at 8.5 with PointsBet, which currently has the best odds for the Over at -105, while BetMGM currently has the best odds for the Under at -110.

As always, check out the sportsbooks you can bet with in your state for the best MLB odds and lines.

According to DimersBOT, the Orioles (+1.5) are a 54% chance of covering the run line, while the Over/Under total of 8.5 runs is a 51% chance of going Under.

More: Live Win Probabilities for All Major Sports

Best Bets for Orioles vs. Cardinals

• Run Line: Orioles +1.5 @ -118 via FanDuel Sportsbook (54% probability)
• Moneyline: Orioles @ +184 via FanDuel Sportsbook
• Total: Under 8.5 @ -110 via BetMGM (51% probability)

Dimers' best bets are based on complex simulations and wagering intelligence to bring you the best possible plays 24/7.

While the Cardinals are more likely to win the game, according to DimersBOT, taking the Orioles moneyline is the best option because of the edge identified when comparing our data-led probabilities to the sportsbooks' odds currently on offer.

Taking advantage of the edges published on Dimers is pivotal to achieving long-term profitability as a sports bettor.

Orioles vs. Cardinals Betting Guide

Use our interactive widget below to see the latest Moneyline, Over/Under and Run Line probabilities and odds for Baltimore vs. St Louis, and click or tap on See Matchup for more.

Dimers has full betting coverage of Thursday's Orioles-Cardinals matchup, including pregame predictions, top betting picks, and live win probabilities.

Don't forget, DimersBOT updates frequently, so keep checking this article for any changes to our betting analysis ahead of Orioles vs. Cardinals on Thursday May 12, 2022.

Risk-Free Bet for Orioles vs. Cardinals

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All you need to do is click or tap on this exclusive FanDuel Sportsbook link and create an account – it's easy and takes less than 2 minutes.

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Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.

Orioles vs. Cardinals 2022 Game Info

Thursday's game between the Cardinals and Orioles at Busch Stadium will commence at 1:15PM ET.

• Date: Thursday May 12, 2022
• Time: 1:15PM ET / 10:15AM PT
• Venue: Busch Stadium

Looking to join an online sportsbook and start betting on MLB? Check out the top sportsbook offers in your state.

What other MLB games are on today?

Now you've got the 411 on Orioles vs. Cardinals, check out the latest betting analysis for all upcoming MLB games in our MLB Bet Hub. There you can find probabilities and odds, and our best bets for each and every MLB matchup.

Want a pick for the Run Line? You got it. How about the Over/Under? Yup, got that too. The Moneyline? Yes sir. And these picks are good, I mean REALLY good. Take a look now!

Finally, Dimers' MLB Futures page is our in-house approach to revealing who will win the 2022 World Series, with our data-led probabilities matched against the best odds to win the World Series.