Orioles vs. Cardinals Prediction and Odds - May 10, 2022

The St Louis Cardinals and Baltimore Orioles lock horns in MLB at Busch Stadium on Tuesday, starting at 7:45PM ET.

Packy Naughton (0-0, 0.00 ERA) will be on the bump for the Cardinals, while the Orioles will counter with Kyle Bradish (0-1, 5.40 ERA).

Dimers' best betting picks for Orioles vs. Cardinals, plus game predictions and best odds, are detailed in this article.

This Baltimore vs. St Louis betting preview is presented by PointsBet, which has a 5x $100 Risk-Free Bets promo for new users.

Who will win Orioles vs. Cardinals?

Based on high-tech machine learning and data, Dimers.com has simulated Tuesday's Orioles-Cardinals MLB game 10,000 times.

Dimers' independent predictive analytics model, DimersBOT, gives the Cardinals a 64% chance of beating the Orioles.

More: Orioles vs. Cardinals Simulated 10,000 Times

Orioles vs. Cardinals Current Odds

• Run Line: Cardinals -1.5 (+134), Orioles +1.5 (-145)
• Moneyline: Cardinals -154, Orioles +145
• Total: Over/Under 8 (-110/-110)

Run Line, Moneyline and Over/Under

The Cardinals are currently -1.5 favorites versus the Orioles, with +134 at FanDuel Sportsbook the best odds currently available.

For the underdog Orioles (+1.5) to cover the run line, BetMGM has the best odds currently on offer at -145.

FanDuel Sportsbook currently has the best moneyline odds for the Cardinals at -154. That means you can risk $154 to win $100, for a total payout of $254, if they get the W.

Elsewhere, DraftKings Sportsbook currently has the best moneyline odds for the Orioles at +145, where you can bet $100 to profit $145, earning a total payout of $245, if they win.

The Over/Under for total runs scored sits at 8 with Caesars Sportsbook, which currently has the best odds for the Over at -110, as well as the best odds for the Under at -110.

As always, check out all the legal sportbooks available in your state for the best MLB odds and lines.

According to DimersBOT, the Orioles (+1.5) are a 54% chance of covering the run line, while the 8-run Over/Under is a 54% chance of going Over.

More: Predictions for Every MLB Game

Best Bets for Orioles vs. Cardinals

• Run Line: Cardinals -1.5 @ +134 via FanDuel Sportsbook (2.9% edge)
• Moneyline: Cardinals @ -154 via FanDuel Sportsbook (64% probability)
• Total: Over 8 @ -110 via Caesars Sportsbook (54% probability)

Dimers' best bets are based on world-class simulations and wagering intelligence to bring you the best possible plays 24/7.

Although the Orioles are more likely to cover the run line, our best bet of Cardinals -1.5 is based on the chance of that happening, according to DimersBOT, and the best odds available.

Orioles vs. Cardinals Betting Guide

Use our dynamic widget below to see the latest Moneyline, Over/Under and Run Line probabilities and odds for Baltimore vs. St Louis, and click or tap on See Matchup to reveal more.

Dimers has full coverage of Tuesday's Orioles-Cardinals matchup, including pregame predictions, free picks, and live win probabilities.

Don't forget, DimersBOT updates regularly, so keep checking this article for the latest betting insights ahead of Orioles vs. Cardinals on Tuesday May 10, 2022.

Risk-Free Bet for Orioles vs. Cardinals

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All you need to do is click or tap on this exclusive FanDuel Sportsbook link and create a new account – it's easy and takes less than 2 minutes.

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Orioles vs. Cardinals 2022 Game Info

Tuesday's game between the Cardinals and Orioles at Busch Stadium is scheduled to start at 7:45PM ET.

• Date: Tuesday May 10, 2022
• Time: 7:45PM ET / 4:45PM PT
• Venue: Busch Stadium

Want to join an online sportsbook and start betting on MLB? Check out the top sports betting bonus offers in your state.

What other MLB games are on today?

Now you've got the 411 on Orioles vs. Cardinals, get the latest betting analysis for all upcoming MLB games in Dimers' MLB Bet Hub. There you can find probabilities and odds, and our best bets for every single MLB matchup.

Want a pick for the Run Line? You got it. How about the Over/Under? Yup, got that too. The Moneyline? Yes sir. And these picks are good, I mean REALLY good. Take a look now!

Lastly, Dimers' Baseball Futures page is our in-house approach to determining who will win the 2022 World Series, with our data-led probabilities paired with the best odds on the market.