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Orioles vs. Blue Jays Prediction and Odds - Sep 16, 2022

The Toronto Blue Jays face the Baltimore Orioles in MLB action at Rogers Centre on Friday, beginning at 7:07PM ET.
Trevor Richards (3-2, 5.59 ERA) will be on the bump for the Blue Jays, while the Orioles are going with Jordan Lyles (10-10, 4.62 ERA).
Dimers' free betting picks for Orioles vs. Blue Jays, plus game predictions and betting odds, are featured in this article.
Who will win Orioles vs. Blue Jays?
Based on cutting-edge machine learning and data, Dimers.com has simulated Friday's Orioles-Blue Jays MLB game 10,000 times.
Dimers' leading predictive analytics model, DimersBOT, currently gives the Blue Jays a 61% chance of getting the W against the Orioles.
More: Orioles vs. Blue Jays Simulated 10K Times
Orioles vs. Blue Jays Odds
- Run Line: Blue Jays -1.5 (+122), Orioles +1.5 (-140)
- Moneyline: Blue Jays -160, Orioles +140
- Total: Over/Under 8.5 (-120/+100)
Run Line, Moneyline and Over/Under
The Blue Jays are -1.5 favorites against the Orioles, with +122 at Caesars Sportsbook the best odds currently available.
For the underdog Orioles (+1.5) to cover the run line, DraftKings Sportsbook has the best odds currently on offer at -140.
BetMGM currently has the best moneyline odds for the Blue Jays at -160, which means you can risk $160 to win $100, for a total payout of $260, if they get the W.
Elsewhere, DraftKings Sportsbook currently has the best moneyline odds for the Orioles at +140, where you can bet $100 to profit $140, earning a total payout of $240, if they win.
The Over/Under sits at 8.5 with BetMGM, which currently has the best odds for the Over at -120, as well as the best odds for the Under at +100.
As always, check out the sportsbooks you have access to in your state for the best MLB odds and lines.
According to DimersBOT, the Orioles (+1.5) are a 56% chance of covering the run line, while the 8.5-run Over/Under is a 59% chance of going Over.
More: Track Your Bets via Dimers' Bet Center
Best Bets for Orioles vs. Blue Jays
- Run Line: Blue Jays -1.5 @ +122 via Caesars Sportsbook
- Moneyline: Blue Jays @ -160 via BetMGM (61% probability)
- Total: Over 8.5 @ -120 via BetMGM (59% probability) 🔥
If you see a 🔥, you know it's one of Dimers' best bets of the day across all sports.
Dimers' best bets are based on world-class modeling and wagering expertise to help you make smarter decisions with the legal sportsbooks in your state.
Although the Orioles are more likely to cover the run line, our best bet of Blue Jays -1.5 is based on the likelihood of that happening, according to DimersBOT, and the best odds available.
Orioles vs. Blue Jays Prediction
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Dimers has full coverage of Friday's Orioles-Blue Jays matchup, including pregame predictions, top betting picks, and live win probabilities.
Remember, DimersBOT updates often, so check this article for any changes to our betting insights ahead of Orioles vs. Blue Jays on Friday September 16, 2022.
Orioles vs. Blue Jays 2022 Game Info
Friday's action between the Blue Jays and Orioles at Rogers Centre is scheduled to begin at 7:07PM ET.
- Who: Baltimore Orioles vs. Toronto Blue Jays
- Date: Friday September 16, 2022
- Time: 7:07PM ET / 4:07PM PT
- Venue: Rogers Centre
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