Orioles vs. Athletics Prediction and Odds - Apr 20, 2022

The Oakland Athletics and Baltimore Orioles meet in MLB at Oakland Coliseum on Wednesday, starting at 6:07PM EDT.

The Athletics will send Daulton Jefferies (1-1, 1.93 ERA) to the mound, while the Orioles will counter with Jordan Lyles (0-1, 5.23 ERA).

Dimers' free betting picks for Orioles vs. Athletics, plus game predictions and best odds, are detailed in this article.

Who will win Orioles vs. Athletics?

Using state-of-the-art computer power and data, Dimers.com has simulated Wednesday's Orioles-Athletics MLB game 10,000 times.

Dimers' renowned predictive analytics model, DimersBOT, currently can't split the two teams, giving both the Orioles and Athletics a 50% chance of winning the game.

More: Orioles vs. Athletics Simulated 10,000 Times

Orioles vs. Athletics Odds

• Run Line: Athletics -1.5 (+155), Orioles +1.5 (-170)
• Moneyline: Athletics -125, Orioles +110
• Total: Over/Under 8 (+100/-115)

Run Line, Moneyline and Over/Under

The Athletics are listed as -1.5 favorites against the Orioles, with +155 at FanDuel Sportsbook the best odds currently available.

For the underdog Orioles (+1.5) to cover the run line, DraftKings Sportsbook has the best odds currently on offer at -170.

PointsBet currently has the best moneyline odds for the Athletics at -125, which means you can risk $125 to win $100, for a total payout of $225, if they get the W.

Elsewhere, DraftKings Sportsbook currently has the best moneyline odds for the Orioles at +110, where you can bet $100 to profit $110, earning a total payout of $210, if they win.

The Over/Under sits at 8 with DraftKings Sportsbook, which currently has the best odds for the Over at +100, while FanDuel Sportsbook currently has the best odds for the Under at -115.

As always, make sure you check all the online sportsbooks that are available in your state for the best MLB odds and lines.

According to DimersBOT, the Orioles (+1.5) are a 67% chance of covering the run line, while the 8-run Over/Under is a 52% chance of going Over.

More: Live Scores for All Major Sports

Best Bets for Orioles vs. Athletics

• Run Line: Orioles +1.5 @ -170 via DraftKings Sportsbook (67% probability)
• Moneyline: Orioles @ +110 via DraftKings Sportsbook (50% probability)
• Total: Over 8 @ +100 via DraftKings Sportsbook (52% probability)

Dimers' best bets are based on world-class simulations and wagering intelligence to serve you the best possible plays 24/7.

Orioles vs. Athletics Betting Guide

Use our widget below to view the latest Moneyline, Over/Under and Run Line probabilities and odds for Baltimore vs. Oakland, and click or tap on See Matchup to reveal more.

Dimers has full betting coverage of Wednesday's Orioles-Athletics matchup, including pre-game predictions, free betting picks, and live win probabilities.

Remember, DimersBOT updates regularly, so keep checking this article for any changes to our betting analysis ahead of Orioles vs. Athletics on Wednesday April 20, 2022.

Top Betting Offer for Orioles vs. Athletics

Looking for a top online sportsbook offer for Baltimore vs. Oakland? Join Betway now and get a bet risk free up to $1,000 in NJ and PA, and up to $250 in CO, IN and IA, which you can use on Wednesday's Orioles-Athletics game.

All you need to do is click or tap on this exclusive Betway link and create an account – it's easy and takes no time at all.

Then, deposit funds and place a bet up to $1,000 in NJ and PA, and up to $250 in CO, IN and IA on Orioles vs. Athletics. If your bet doesn't win, Betway will refund it in site credit!

This promo is available to all new Betway users – no promo code required!

Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.

Orioles vs. Athletics 2022 Game Info

When do the Athletics play the Orioles?

• Date: Wednesday April 20, 2022
• Time: 6:07PM EDT / 3:07PM PDT
• Venue: Oakland Coliseum

Want to join an online sportsbook and start betting on MLB now? We've got access to the best available sign-up offers in every legal betting state.

Want more MLB previews like this?

So, you liked our Orioles vs. Athletics betting predictions? Awesome. Did you know our MLB Betting News page has a detailed betting preview for every MLB game as soon as the sportsbooks release their odds?

That's right, our predictive analytics model then compares those odds against its own probabilities to find edges in the markets, which allows us to write the most reliable MLB betting previews and beat the public and the sportsbooks to the punch.

It's only a click away, so why not see for yourself?

Lastly, Dimers' MLB Futures page is our in-house approach to revealing who will win the 2022 World Series, with our data-led probabilities paired with the best odds to win the World Series.