Ole Miss vs. St. John's prediction: St. John's favored to win men's college basketball matchup [12/6/2025]

St. John's will face Ole Miss in men's college basketball action at Madison Square Garden on Saturday, commencing at 8:00PM ET.

Based on updated simulations, Dimers' proven college basketball model predicts St. John's as the most likely winner of the Ole Miss vs. St. John's game.

This article offers further insights into Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

Ole Miss vs. St. John's prediction: Who will win and cover?

Using trusted machine learning and data, we have simulated the outcome of Saturday's NCAA basketball game between Ole Miss and St. John's 10,000 times as part of our men's college basketball predictions coverage.

Our famous predictive model currently gives St. John's an 87% chance of defeating Ole Miss. Our predicted final score has St. John's winning 82-70.

According to our model, Ole Miss (+13.5) has a 53% chance of covering the spread, while the over/under total of 151.5 points has a 53% chance of going over.

Ole Miss vs. St. John's odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Ole Miss vs. St. John's picks and best bet

After matching our probabilities against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: