Oklahoma State vs. Oklahoma prediction: Oklahoma favored to win men's college basketball matchup [12/13/2025]

Oklahoma will take on Oklahoma State in men's college basketball action at Paycom Center on Saturday, commencing at 1:00PM ET.

Based on the latest simulations, Dimers' advanced college basketball model predicts Oklahoma as the most likely winner of the Oklahoma State vs. Oklahoma game.

This article offers further insights into Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

Oklahoma State vs. Oklahoma prediction: Who will win and cover?

Using innovative machine learning and statistical analysis, we have simulated the result of Saturday's NCAA basketball game between Oklahoma State and Oklahoma 10,000 times as part of our men's college basketball predictions coverage.

Our famous predictive model currently gives Oklahoma a 64% chance of beating Oklahoma State. Our predicted final score has Oklahoma winning 82-78.

According to our model, Oklahoma (-2.5) has a 59% chance of covering the spread, while the 169.5-point over/under has a 55% chance of staying under.

Oklahoma State vs. Oklahoma odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Oklahoma State vs. Oklahoma picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: