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NY Red Bulls vs. D.C. United prediction, odds, MLS picks [4/22/2026]
Updated: | First published:
Written by Nick Slade, Chief Content Officer
Get NY Red Bulls vs D.C. United predictions for MLS Wednesday.
The NY Red Bulls will face D.C. United in MLS action at Sports Illustrated Stadium on Wednesday, beginning at 7:30 PM ET.
Based on updated simulation results, Dimers' proven MLS model predicts NY Red Bulls as the most likely winner of the NY Red Bulls vs. D.C. United game.
This article offers a closer look at Wednesday's match, including best bets and picks.
NY Red Bulls vs. D.C. United prediction: Who will win?
Using innovative machine learning and data analysis, we have simulated the outcome of Wednesday's MLS game between NY Red Bulls and D.C. United, forming part of our MLS predictions coverage.
Our independent predictive model indicates a 60.3% chance of NY Red Bulls winning, an 18.2% chance for D.C. United, and a 21.5% chance of a draw.
Additionally, the over/under total of 2.5 goals has a 56% chance of going over, according to our model.
NY Red Bulls vs. D.C. United odds
We have sourced the best MLS odds in America for this game, which are listed here:
Moneyline
| NY Red Bulls | D.C. United | Draw |
|---|---|---|
| -110 | +290 | +280 |
Total Goals
| Over 2.5 | Under 2.5 |
|---|---|
| -150 | +100 |
All odds are correct at the time of publication and are subject to change.
NY Red Bulls vs. D.C. United picks and best bet
After matching our probabilities against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Moneyline | NY Red Bulls | -110 |
| Total Goals | Over 2.5 | -150 |
According to our best MLS bets, the top play to make on this game is NY Red Bulls to win.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
NY Red Bulls vs. D.C. United: Correct score predictions
The top three most likely final scores, according to our model, are listed below, with a 1-0 NY Red Bulls win being the most probable:
| Final Score | Probability |
|---|---|
| NYR 1-0 DCU | 10.5% |
| NYR 1-1 DCU | 10.2% |
| NYR 2-0 DCU | 10.2% |
NY Red Bulls vs. D.C. United game-day updates and essential details
Wednesday's matchup between NY Red Bulls and D.C. United in MLS at Sports Illustrated Stadium is scheduled to start at 7:30 PM ET.
- Who: NY Red Bulls vs. D.C. United
- Date: Wednesday, April 22, 2026
- Time: 7:30 PM ET/4:30PM PT
- Venue: Sports Illustrated Stadium
World Cup 2026 watch: John Tolkin (USA)
NY Red Bulls left-back John Tolkin is one to watch for USMNT fans at the moment as anticipation grows in the lead up to the FIFA World Cup 2026, with rising interest in World Cup predictions and early discussions about who will win the World Cup. With the United States placed alongside Australia, Paraguay, and Türkiye in Group D next year, Tolkin's form will be tracked closely.
Conclusion
According to our computer model, NY Red Bulls have a 60.3% win probability on Wednesday, D.C. United has an 18.2% win probability, and there is a 21.5% chance that the game will end in a draw.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
Nick Slade, with nearly two decades of experience, is the Chief Content Officer at Cipher Sports Technology Group, overseeing content for Dimers. He specializes in soccer, NBA, and NHL betting, leveraging predictive analytics and machine learning to provide accurate betting insights.
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