Notre Dame vs. TCU prediction: Why TCU is favored to win men's college basketball matchup [12/5/2025]

TCU will square off with Notre Dame in men's college basketball action at Ed and Rae Schollmaier Arena on Friday, starting at 8:00PM ET.

Based on the latest simulation results, Dimers' advanced college basketball model projects TCU as the most likely winner of the Notre Dame vs. TCU game.

This article offers further insights into Friday's matchup, including an expanded look at the predicted score, best bets and picks.

Notre Dame vs. TCU prediction: Who will win and cover?

Using trusted machine learning and data analysis, we have simulated the outcome of Friday's NCAA basketball matchup between Notre Dame and TCU 10,000 times as part of our men's college basketball predictions coverage.

Our leading predictive model currently gives TCU a 76% chance of beating Notre Dame. Our predicted final score has TCU winning 73-66.

According to our model, Notre Dame (+7.5) has a 53% chance of covering the spread, while the over/under total of 139.5 points has a 52% chance of going over.

Notre Dame vs. TCU odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Notre Dame vs. TCU picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: