Northern Iowa vs. Saint Mary's prediction: Saint Mary's favored to win men's college basketball matchup [12/22/2025]

Saint Mary's will square off with Northern Iowa in men's college basketball action at University Credit Union Pavilion on Monday, starting at 10:00 PM ET.

Based on updated simulations, Dimers' proven college basketball model predicts Saint Mary's as the most likely winner of the Northern Iowa vs. Saint Mary's game.

This article offers further insights into Monday's matchup, including an expanded look at the predicted score, best bets and picks.

Northern Iowa vs. Saint Mary's prediction: Who will win and cover?

Using powerful machine learning and data, we have simulated the outcome of Monday's NCAA basketball matchup between Northern Iowa and Saint Mary's 10,000 times as part of our men's college basketball predictions coverage.

Our famous predictive model gives Saint Mary's a 90% chance of defeating Northern Iowa. Our predicted final score has Saint Mary's winning 73-61.

According to our model, Saint Mary's (-11.5) has a 56% chance of covering the spread, while the 132.5-point over/under has a 55% chance of going over.

Northern Iowa vs. Saint Mary's odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Northern Iowa vs. Saint Mary's picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

According to our men's college basketball best bets, the top play to make on this game is Saint Mary's -11.5 at the spread.

Northern Iowa vs. Saint Mary's game-day updates and essential details

Monday's men's college basketball action between Saint Mary's and Northern Iowa at University Credit Union Pavilion is scheduled to commence at 10:00 PM ET.

• Who: Northern Iowa vs. Saint Mary's
• Date: Monday, December 22, 2025
• Time: 10:00 PM ET/7:00PM PT
• Venue: University Credit Union Pavilion

Conclusion

We predict Saint Mary's, with a 90% win probability, will likely beat Northern Iowa on Monday.

AI and automation have enhanced this article to quickly deliver accurate Northern Iowa vs. Saint Mary's insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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