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Northeastern vs. Syracuse prediction: Syracuse favored to win men's college basketball matchup [12/20/2025]
Get Northeastern vs Syracuse predictions for college basketball Saturday.

Syracuse will square off with Northeastern in men's college basketball action at JMA Wireless Dome on Saturday, commencing at 4:00 PM ET.
Based on the latest simulation results, Dimers' proven college basketball model predicts Syracuse as the most likely winner of the Northeastern vs. Syracuse game.
This article offers a closer look at Saturday's matchup, including an expanded look at the predicted score, best bets and picks.
Northeastern vs. Syracuse prediction: Who will win and cover?
Using innovative machine learning and data, we have simulated the outcome of Saturday's NCAA basketball game between Northeastern and Syracuse 10,000 times as part of our men's college basketball predictions coverage.
Our famous predictive model currently gives Syracuse a 92% chance of beating Northeastern. Our predicted final score has Syracuse winning 78-63.
According to our model, the bookmakers have got it right, and Northeastern and Syracuse each have a 50% chance of covering the spread, while the over/under total of 140.5 points has a 52% chance of staying under.
Northeastern vs. Syracuse odds
We have sourced the best men's college basketball odds in America for this game, which are listed here:
| Bet Type | Northeastern | Syracuse |
|---|---|---|
| Spread | +14.5 (-108) | -14.5 (-110) |
| Moneyline | +860 | -1350 |
| Total | o140.5 (-115) | u140.5 (-105) |
All odds are correct at the time of publication and are subject to change.
Northeastern vs. Syracuse picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Northeastern +14.5 | -108 |
| Moneyline | Syracuse | -1350 |
| Total | Under 140.5 | -105 |
According to our men's college basketball best bets, the top play to make on this game is Under 140.5 total points.
Northeastern vs. Syracuse game-day updates and essential details
Saturday's men's college basketball game between Syracuse and Northeastern at JMA Wireless Dome is scheduled to start at 4:00 PM ET.
- Who: Northeastern vs. Syracuse
- Date: Saturday, December 20, 2025
- Time: 4:00 PM ET/1:00PM PT
- Venue: JMA Wireless Dome
Conclusion
We predict Syracuse, with a 92% win probability, will likely beat Northeastern on Saturday.
AI and automation have enhanced this article to quickly deliver accurate Northeastern vs. Syracuse insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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