UNC Wilmington vs. Louisiana-Lafayette prediction: North Carolina-Wilmington favored to win men's college basketball matchup [12/6/2025]

Louisiana-Lafayette will face the favored UNC Wilmington in men's college basketball action at Cajundome on Saturday, commencing at 4:00PM ET.

Based on updated simulations, Dimers' proven college basketball model predicts North Carolina-Wilmington as the most likely winner of the UNC Wilmington vs. Louisiana-Lafayette game.

This article offers an expanded analysis of Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

UNC Wilmington vs. Louisiana-Lafayette prediction: Who will win and cover?

Using innovative machine learning and data analysis, we have simulated the outcome of Saturday's NCAA basketball game between UNC Wilmington and Louisiana-Lafayette 10,000 times as part of our men's college basketball predictions coverage.

Our famous predictive model gives North Carolina-Wilmington an 88% chance of defeating Louisiana-Lafayette. Our predicted final score has North Carolina-Wilmington winning 71-60.

According to our model, Louisiana-Lafayette (+11.5) has a 52% chance of covering the spread, while the over/under total of 127.5 points has a 55% chance of going over.

UNC Wilmington vs. Louisiana-Lafayette odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

UNC Wilmington vs. Louisiana-Lafayette picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: