Mets vs. Nationals prediction: Why Mets are favored to win Wednesday's MLB matchup [5/20/2026]

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Written by Dave Garofolo

Get New York Mets vs Washington Nationals predictions for MLB Wednesday.

New York Mets-Washington Nationals Predictions and Game Preview.
New York Mets vs. Washington Nationals MLB prediction for Wednesday, May 20, 2026.

The Washington Nationals will square off with the New York Mets, in what is expected to be a close MLB game, at Nationals Park on Wednesday, starting at 6:45 PM ET.

The Nationals will send Zack Littell (2-4, 6.10 ERA) to the mound, pitting him against Zach Thornton (0-0, 0.00 ERA) for the Mets.

Based on the latest simulations, Dimers' advanced MLB model gives the Mets a slight edge with a 54% win probability over the Nationals.

This article offers a closer look at Wednesday's Mets vs. Nationals matchup, including best bets and picks.

Mets vs. Nationals prediction: Who will win and cover?

Using trusted machine learning and statistical analysis, we have simulated the result of Wednesday's MLB game between the Mets and Nationals, forming part of our MLB predictions coverage.

Our famous predictive model currently gives the Mets a 54% chance of beating the Nationals.

According to our model, the Nationals (+1.5) have a 57% chance of covering the run line, while the 9.5-run over/under has a 51% chance of going over.

 

Mets vs. Nationals odds [5/20/2026]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type Mets Nationals
Run Line -1.5 (+125) +1.5 (-146)
Moneyline -125 +110
Total o9.5 (-102) u9.5 (-110)

All odds are correct at the time of publication and are subject to change.

Mets vs. Nationals picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Run Line Mets -1.5 +125
Moneyline Mets -125
Total Over 9.5 -102

According to our MLB best bets, the top play to make on this game is Over 9.5 total runs.

These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.

 

Mets vs. Nationals game-day updates and essential details

Wednesday's MLB matchup between the Nationals and Mets at Nationals Park is scheduled to start at 6:45 PM ET.

Conclusion

We predict the Mets, with a 54% win probability, will likely beat the Nationals in Wednesday's MLB matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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