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New York City vs. St Louis City prediction, odds, MLS picks [4/4/2026]
Updated: | First published:
Written by Nick Slade, Chief Content Officer
Get New York City vs St Louis City predictions for MLS Saturday.
NY City will face St Louis City in MLS action at Yankee Stadium on Saturday, beginning at 7:30 PM ET.
Based on updated simulation results, Dimers' proven MLS model projects NY City as the most likely winner of the NY City vs. St Louis City game.
This article offers a closer look at Saturday's match, including best bets and picks.
New York City vs. St Louis City prediction: Who will win?
Using trusted machine learning and data, we have simulated the outcome of Saturday's MLS game between NY City and St Louis City, forming part of our MLS predictions coverage.
Our famous predictive model currently indicates a 60.3% chance of NY City winning, an 18.9% chance for St Louis City, and a 20.8% chance of a draw.
Additionally, the over/under total of 2.5 goals has a 60% chance of going over, according to our model.
New York City vs. St Louis City odds
We have researched the best MLS odds in America for this game, which are listed here:
Moneyline
| NY City | St Louis City | Draw |
|---|---|---|
| -130 | +350 | +280 |
Total Goals
| Over 2.5 | Under 2.5 |
|---|---|
| -125 | +100 |
All odds are correct at the time of publication and are subject to change.
New York City vs. St Louis City picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Moneyline | NY City | -130 |
| Total Goals | Over 2.5 | -125 |
According to our MLS best bets, the top play to make on this game is Over 2.5 total goals.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
New York City vs. St Louis City: Correct score predictions
The top three most likely final scores, according to our model, are listed below, with a 2-1 NY City win being the most probable:
| Final Score | Probability |
|---|---|
| NYC 2-1 STL | 9.9% |
| NYC 1-1 STL | 9.6% |
| NYC 2-0 STL | 9.3% |
New York City vs. St Louis City game-day updates and essential details
Saturday's matchup between NY City and St Louis City in MLS at Yankee Stadium is scheduled to begin at 7:30 PM ET.
- Who: New York City vs. St Louis City
- Date: Saturday, April 4, 2026
- Time: 7:30 PM ET/4:30PM PT
- Venue: Yankee Stadium
World Cup 2026 watch: Matt Freese (USA)
NY City goalkeeper Matt Freese is a key name to follow for USMNT supporters this year as anticipation grows ahead of the FIFA World Cup 2026—a tournament sparking interest in World Cup news and early conversation about who will win the World Cup. With the United States drawn against Australia, Paraguay, and one of Türkiye, Romania, Slovakia, or Kosovo in Group D next year, Freese's club form will be monitored closely.
Conclusion
According to our computer model, NY City has a 60.3% win probability on Saturday, St Louis City has an 18.9% win probability, and there is a 20.8% chance that the game will end in a draw.
AI and automation have enhanced this article to quickly deliver accurate NY City vs. St Louis City insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice, head to our responsible gambling hub.
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Nick Slade, with nearly two decades of experience, is the Chief Content Officer at Cipher Sports Technology Group, overseeing content for Dimers. He specializes in soccer, NBA, and NHL betting, leveraging predictive analytics and machine learning to provide accurate betting insights.
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