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Brewers vs. Cardinals prediction: Close contest projected after new data released for Tuesday's MLB matchup [5/5/2026]
Get Milwaukee Brewers vs St. Louis Cardinals predictions for MLB Tuesday.

The St. Louis Cardinals and Milwaukee Brewers will meet in MLB action at Busch Stadium on Tuesday, starting at 7:45 PM ET.
Andre Pallante (3-2, 3.73 ERA) will get the ball for the Cardinals, pitting him against Brandon Sproat (0-2, 6.75 ERA) for the Brewers.
Based on updated simulations, Dimers' proven MLB model gives an equal chance for both both teams to win the Brewers-Cardinals matchup.
This article offers a closer look at Tuesday's Brewers vs. Cardinals matchup, including best bets and picks.
Brewers vs. Cardinals prediction: Who will win?
Our leading predictive model currently can't split the two teams, giving both the Brewers and Cardinals a 50% chance of winning the game.
According to our model, the over/under total of 7.5 runs has a 54% chance of going over.
Brewers vs. Cardinals odds [5/5/2026]
We have sourced the best MLB odds in America for this game, which are listed here:
| Bet Type | Brewers | Cardinals |
|---|---|---|
| Moneyline | -106 | -110 |
| Total | o7.5 (-115) | u7.5 (-104) |
All odds are correct at the time of publication and are subject to change.
Brewers vs. Cardinals picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Moneyline | Brewers | -106 |
| Total | Over 7.5 | -115 |
According to our MLB best bets, the top play to make on this game is Over 7.5 total runs.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Brewers vs. Cardinals game-day updates and essential details
Tuesday's MLB action between the Cardinals and Brewers at Busch Stadium is scheduled to commence at 7:45 PM ET.
- Who: Milwaukee Brewers vs. St. Louis Cardinals
- Date: Tuesday, May 5, 2026
- Time: 7:45 PM ET/4:45PM PT
- Venue: Busch Stadium
Conclusion
We predict a close game between the Brewers and Cardinals on Tuesday, with each team having a 50% chance of winning.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
