Brewers vs. Twins prediction: Why Milwaukee is favored to win Saturday's MLB matchup [5/16/2026]

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Written by Jason Bevilacqua

Get Milwaukee Brewers vs Minnesota Twins predictions for MLB Saturday.

Milwaukee Brewers-Minnesota Twins Predictions and Game Preview.
Milwaukee Brewers vs. Minnesota Twins MLB prediction for Saturday, May 16, 2026.

The Minnesota Twins and Milwaukee Brewers are scheduled to meet in MLB action at Target Field on Saturday, starting at 7:10 PM ET.

Connor Prielipp (1-1, 3.32 ERA) will start for the Twins, while the Brewers are going with Logan Henderson (0-1, 4.15 ERA).

Based on updated simulations, Dimers' advanced MLB model gives the Brewers a slight edge with a 52% win probability over the Twins.

This article offers a closer look at Saturday's Brewers vs. Twins matchup, including best bets and picks.

Brewers vs. Twins prediction: Who will win and cover?

Using powerful machine learning and data, we have simulated the result of Saturday's MLB matchup between the Brewers and Twins, forming part of our MLB predictions coverage.

Our famous predictive model gives the Brewers a 52% chance of beating the Twins.

According to our model, the Twins (+1.5) have a 59% chance of covering the run line, while the 8.5-run over/under has a 54% chance of going over.

 

Brewers vs. Twins odds [5/16/2026]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type Brewers Twins
Run Line -1.5 (+132) +1.5 (-155)
Moneyline -124 +106
Total o8.5 (-102) u8.5 (-112)

All odds are correct at the time of publication and are subject to change.

Brewers vs. Twins picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Run Line Twins +1.5 -155
Moneyline Twins +106
Total Over 8.5 -102

According to our MLB best bets, the top play to make on this game is Over 8.5 total runs.

These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.

 

Brewers vs. Twins game-day updates and essential details

Saturday's MLB action between the Twins and Brewers at Target Field is scheduled to start at 7:10 PM ET.

Conclusion

We predict the Brewers, with a 52% win probability, will likely beat the Twins in Saturday's MLB matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

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Written by
Jason Bevilacqua
Head of Content and Communities

Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.

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