Middle Tennessee vs. Houston prediction: Houston favored to win men's college basketball matchup [12/29/2025]

Houston will take on Middle Tennessee in men's college basketball action at Fertitta Center on Monday, beginning at 8:00 PM ET.

Based on the latest simulation results, Dimers' proven college basketball model projects Houston as the most likely winner of the Middle Tennessee vs. Houston game.

This article offers a closer look at Monday's matchup, including an expanded look at the predicted score, best bets and picks.

Middle Tennessee vs. Houston prediction: Who will win and cover?

Using innovative machine learning and data, we have simulated the result of Monday's NCAA basketball game between Middle Tennessee and Houston 10,000 times as part of our men's college basketball predictions coverage.

Our famous predictive model currently gives Houston a 99% chance of defeating Middle Tennessee. Our predicted final score has Houston winning 83-54.

According to our model, Houston (-28.5) has a 51% chance of covering the spread, while the 135.5-point over/under has a 54% chance of going over.

Middle Tennessee vs. Houston odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Middle Tennessee vs. Houston picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: