Mets vs. Cardinals Prediction and Odds - Apr 27, 2022

The St Louis Cardinals face the New York Mets in MLB action at Busch Stadium on Wednesday, beginning at 1:15PM ET.

Steven Matz (2-1, 5.27 ERA) will start on the mound for the Cardinals, up against Carlos Carrasco (1-0, 1.47 ERA) for the Mets.

Dimers' free betting picks for Mets vs. Cardinals, plus game predictions and best odds, are featured below.

Who will win Mets vs. Cardinals?

Using advanced machine learning and data, Dimers.com has simulated Wednesday's Mets-Cardinals MLB matchup 10,000 times.

Dimers' renowned predictive analytics model, DimersBOT, gives the Cardinals a 51% chance of beating the Mets.

More: Mets vs. Cardinals Simulated 10K Times

Mets vs. Cardinals Game Odds

• Run Line: Cardinals +1.5 (-165), Mets -1.5 (+150)
• Moneyline: Cardinals +100, Mets -115
• Total: Over/Under 7 (-120/+105)

Run Line, Moneyline and Over/Under

The Cardinals are +1.5 underdogs versus the Mets, with -165 at PointsBet the best odds currently available.

For the favored Mets (-1.5) to cover the run line, DraftKings Sportsbook has the best odds currently on offer at +150.

BetMGM currently has the best moneyline odds for the Cardinals at +100. That means you can risk $100 to win $100, for a total payout of $200, if they get the W.

Elsewhere, PointsBet currently has the best moneyline odds for the Mets at -115, where you can risk $115 to win $100, for a total payout of $215, if they come out on top.

The Over/Under sits at 7 with BetMGM, which currently has the best odds for the Over at -120, while DraftKings Sportsbook currently has the best odds for the Under at +105.

As always, make sure you check all the legal sportbooks that are available in your state for the best MLB odds and lines.

According to DimersBOT, the Cardinals (+1.5) are a 64% chance of covering the run line, while the Over/Under total of 7 runs is a 55% chance of going Over.

More: Live Scores for All Major Sports

Best Bets for Mets vs. Cardinals

• Run Line: Cardinals +1.5 @ -165 via PointsBet (64% probability)
• Moneyline: Cardinals @ +100 via BetMGM (51% probability)
• Total: Over 7 @ -120 via BetMGM (55% probability)

Dimers' best bets are based on detailed simulations and betting intelligence to help you make more informed decisions with the legal sportsbooks in the USA.

Mets vs. Cardinals Probabilities

Use our widget below to see up-to-date Moneyline, Over/Under and Run Line probabilities and odds for NY Mets vs. St Louis, and click or tap on See Matchup for more.

Dimers has full betting coverage of Wednesday's Mets-Cardinals matchup, including pregame predictions, free betting picks, and live scores.

Don't forget, DimersBOT updates frequently, so keep an eye on this page for any changes to our betting analysis before Mets vs. Cardinals on Wednesday April 27, 2022.

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Mets vs. Cardinals 2022 Game Info

When do the Cardinals play the Mets?

• Date: Wednesday April 27, 2022
• Time: 1:15PM ET / 10:15AM PT
• Venue: Busch Stadium

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What MLB games are on today?

Now you've got the 411 on Mets vs. Cardinals, see the latest betting analysis for all upcoming MLB games in Dimers' MLB Bet Hub. There you can find probabilities and odds, as well as our best bets for every single MLB matchup.

Want a pick for the Run Line? You got it. How about the Over/Under? Yup, got that too. The Moneyline? Yes sir. And these picks are good, I mean REALLY good. Take a look now!

Lastly, Dimers' MLB Futures page is our in-house approach to revealing who will win the 2022 World Series, with our data-led probabilities paired with the best odds to win the World Series.