Men's college basketball picks today: Wednesday's best bets include Loyola Chicago vs. San Francisco play [12/17/2025]

Today’s men's college basketball picks for December 17, 2025 are here, with Loyola Chicago vs. San Francisco among the top plays identified by our model across Wednesday’s men's college basketball schedule.

Dimers’ predictive analytics engine runs 24/7, going over the latest men's college basketball odds to discover top betting edges. The result? Data-backed plays that help Dimers Pro members make smarter decisions.

List of NCAAM picks tonight [12/17, updated 9:32PM ET]

Below, you’ll find today’s top 10 men's college basketball bets, ranked by edge for Wednesday, December 17, 2025.

San Francisco -10.5 (-110)

• Edge: 7.2%
• Probability: 59.6%
• Matchup: Loyola Chicago vs. San Francisco (10:00PM ET, Wednesday)

Our model has identified value on San Francisco -10.5 at -110 odds. A 59.6% probability produces an edge of 7.2%, making this the strongest play for today's men's college basketball slate.

San Francisco ML (-670)

• Edge: 3.9%
• Probability: 90.9%
• Matchup: Loyola Chicago vs. San Francisco (10:00PM ET, Wednesday)

San Francisco ML carries a 3.9% edge and a probability of 90.9% at -670 odds, according to our model.

Texas-Arlington vs. Stanford over 139.5 points (-105)

• Edge: 3.0%
• Probability: 54.3%
• Matchup: Texas-Arlington vs. Stanford (10:00PM ET, Wednesday)

Texas-Arlington vs. Stanford over 139.5 points at -105 odds shows a 3.0% edge, supported by a 54.3% probability in simulations.

Charleston Southern -10.5 (-102)

• Edge: 5.7%
• Probability: 56.2%
• Matchup: North Florida vs. Charleston Southern (11:00AM ET, Thursday)

A 5.7% edge and 56.2% probability make Charleston Southern -10.5 vs. North Florida at a value play in the North Florida vs. Charleston Southern matchup, per our model.

Tennessee-Martin vs. Tennessee State over 143.5 points (-110)

• Edge: 5.6%
• Probability: 58%
• Matchup: Tennessee-Martin vs. Tennessee State (8:30PM ET, Thursday)

Tennessee-Martin vs. Tennessee State over 143.5 points at -110 odds presents a 5.6% edge, with simulations resulting in a probability of 58%.

Grambling State vs. Norfolk State over 132.5 points (-105)

• Edge: 5.5%
• Probability: 56.7%
• Matchup: Grambling State vs. Norfolk State (7:30PM ET, Thursday)

Our model finds value on over 132.5 points in Grambling State vs. Norfolk State at -105 odds, supported by an edge of 5.5%.

Norfolk State ML (-115)

• Edge: 5.0%
• Probability: 58.5%
• Matchup: Grambling State vs. Norfolk State (7:30PM ET, Thursday)

Our model has uncovered value on Norfolk State ML at -115 odds. A 58.5% probability produces a 5.0% edge, making this a strong play for today's men's college basketball action.

Arkansas-Little Rock +3.5 (-115)

• Edge: 4.9%
• Probability: 58.4%
• Matchup: Arkansas-Little Rock vs. Southern Indiana (8:30PM ET, Thursday)

A 4.9% edge on a 58.4% probability makes Arkansas-Little Rock +3.5 at -115 odds a solid value play in today's Arkansas-Little Rock vs. Southern Indiana matchup.

Norfolk State -1.5 (+100)

• Edge: 4.8%
• Probability: 54.8%
• Matchup: Grambling State vs. Norfolk State (7:30PM ET, Thursday)

Our model projects value on Norfolk State -1.5 at +100 odds. A 54.8% probability produces a 4.8% edge, making Norfolk State the favorable side in Saturday’s matchup.

Bradley vs. Indiana State over 145.5 points (-110)

• Edge: 4.4%
• Probability: 56.8%
• Matchup: Grambling State vs. Norfolk State (7:00PM ET, Thursday)

Rounding out our top 10 bets, Bradley vs. Indiana State over 145.5 points at -110 odds shows a 56.8% probability and a 4.4% edge.

NCAAM best bets summary: Wednesday, 12/17/2025

As of 9:32PM ET, here are our top men's college basketball bets by edge recommended by our model:

Matchup	Bet	Odds	Edge	Probability
Loyola Chicago vs. San Francisco	San Francisco -10.5	-110 @ FanDuel	7.2%	59.6%
Loyola Chicago vs. San Francisco	San Francisco ML	-670 @ FanDuel	3.9%	90.9%
Texas-Arlington vs. Stanford	Over 139.5 Points	-105 @ BetMGM	3.0%	54.3%
North Florida vs. Charleston Southern	Charleston Southern -10.5	-102 @ FanDuel	5.7%	56.2%
Tennessee-Martin vs. Tennessee State	Over 143.5 Points	-110 @ FanDuel	5.6%	58%
Grambling State vs. Norfolk State	Over 132.5 Points	-105 @ BetMGM	5.5%	56.7%
Grambling State vs. Norfolk State	Norfolk State ML	-115 @ BetMGM	5.0%	58.5%
Arkansas-Little Rock vs. Southern Indiana	Arkansas-Little Rock +3.5	-115 @ BetMGM	4.9%	58.4%
Grambling State vs. Norfolk State	Norfolk State -1.5	+100 @ BetMGM	4.8%	54.8%
Bradley vs. Indiana State	Over 145.5 Points	-110 @ FanDuel	4.4%	56.8%

List of upcoming men's college basketball games to bet on now

• Air Force vs. San Diego State (10:00PM ET, Wednesday)
• Texas-Arlington vs. Stanford (10:00PM ET, Wednesday)
• Loyola Chicago vs. San Francisco (10:00PM ET, Wednesday)
• Eastern Washington vs. Washington State (10:00PM ET, Wednesday)
• Arizona State vs. UCLA (10:30PM ET, Wednesday)
• Portland vs. Oregon (11:00PM ET, Wednesday)
• North Florida vs. Charleston Southern (11:00AM ET, Thursday)
• Jackson State vs. Hampton (5:00PM ET, Thursday)
• Coastal Carolina vs. Appalachian State (6:30PM ET, Thursday)
• SIU-Edwardsville vs. Eastern Illinois (6:30PM ET, Thursday)

Conclusion

Our men's college basketball best bets are locked and loaded for December 17, 2025, featuring plays such as San Francisco -10.5 and San Francisco ML. Powered by advanced simulations, these picks are here to boost your betting game.

This article, enhanced by AI and automation, aims to deliver accurate college basketball insights quickly, with human oversight ensuring high editorial quality. Our predictions are based on current data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

All odds and probabilities in this article are correct and accurate at the time of publication.

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