Men's college basketball picks today: Wednesday's best bets include St. Francis (PA) vs. Florida play [12/17/2025]

St. Francis (PA) +45.5 (-110)

• Edge: 9.6%
• Probability: 62%
• Matchup: St. Francis (PA) vs. Florida (6:30PM ET, Wednesday)

Our model has identified value on St. Francis (PA) +45.5 at -110 odds. A 62% probability produces an edge of 9.6%, making this the strongest play for today's men's college basketball slate.

Northern Kentucky ML (-130)

• Edge: 7.7%
• Probability: 64.2%
• Matchup: Oakland vs. Northern Kentucky (7:00PM ET, Wednesday)

Northern Kentucky ML carries a 7.7% edge and a probability of 64.2% at -130 odds, according to our model.

Santa Clara -11.5 (-105)

• Edge: 6.4%
• Probability: 57.6%
• Matchup: North Texas vs. Santa Clara (9:00PM ET, Wednesday)

Santa Clara -11.5 vs. North Texas at -105 odds shows a 6.4% edge, supported by a 57.6% probability in simulations.

Northern Kentucky -1.5 (-110)

• Edge: 6.0%
• Probability: 58.4%
• Matchup: Oakland vs. Northern Kentucky (7:00PM ET, Wednesday)

A 6.0% edge and 58.4% probability make Northern Kentucky -1.5 vs. Oakland at a value play in the Oakland vs. Northern Kentucky matchup, per our model.

Vermont ML (-118)

• Edge: 5.9%
• Probability: 60.1%
• Matchup: Siena vs. Vermont (7:00PM ET, Wednesday)

Vermont ML at -118 odds presents a 5.9% edge, with simulations resulting in a probability of 60.1%.

Arizona State +9.5 (-118)

• Edge: 5.4%
• Probability: 59.5%
• Matchup: Arizona State vs. UCLA (10:30PM ET, Wednesday)

Our model finds value on Arizona State +9.5 at -118 odds, supported by an edge of 5.4%.

Texas State +3.5 (-102)

• Edge: 5.3%
• Probability: 55.8%
• Matchup: Arkansas State vs. Texas State (8:30PM ET, Wednesday)

Our model has uncovered value on Texas State +3.5 at -102 odds. A 55.8% probability produces a 5.3% edge, making this a strong play for today's men's college basketball action.

Campbell +37.5 (-110)

• Edge: 4.6%
• Probability: 57%
• Matchup: Campbell vs. Gonzaga (9:00PM ET, Wednesday)

A 4.6% edge on a 57% probability makes Campbell +37.5 at -110 odds a solid value play in today's Campbell vs. Gonzaga matchup.

Elon +4.5 (-106)

• Edge: 4.0%
• Probability: 55.5%
• Matchup: Richmond vs. Elon (7:00PM ET, Wednesday)

Our model projects value on Elon +4.5 at -106 odds. A 55.5% probability produces a 4.0% edge, making Elon the favorable side in Saturday’s matchup.

East Carolina ML (-160)

• Edge: 4.0%
• Probability: 65.6%
• Matchup: Arkansas State vs. Texas State (7:00PM ET, Wednesday)

Rounding out our top 10 bets, East Carolina to defeat Presbyterian at -160 odds shows a 65.6% probability and a 4.0% edge.

NCAAM best bets summary: Wednesday, 12/17/2025

As of 5:32AM ET, here are our top men's college basketball bets by edge recommended by our model:

Matchup	Bet	Odds	Edge	Probability
St. Francis (PA) vs. Florida	St. Francis (PA) +45.5	-110 @ BetMGM	9.6%	62%
Oakland vs. Northern Kentucky	Northern Kentucky ML	-130 @ DraftKings	7.7%	64.2%
North Texas vs. Santa Clara	Santa Clara -11.5	-105 @ BetMGM	6.4%	57.6%
Oakland vs. Northern Kentucky	Northern Kentucky -1.5	-110 @ BetMGM	6.0%	58.4%
Siena vs. Vermont	Vermont ML	-118 @ BetMGM	5.9%	60.1%
Arizona State vs. UCLA	Arizona State +9.5	-118 @ BetMGM	5.4%	59.5%
Arkansas State vs. Texas State	Texas State +3.5	-102 @ BetMGM	5.3%	55.8%
Campbell vs. Gonzaga	Campbell +37.5	-110 @ BetMGM	4.6%	57%
Richmond vs. Elon	Elon +4.5	-106 @ FanDuel	4.0%	55.5%
Presbyterian vs. East Carolina	East Carolina ML	-160 @ BetMGM	4.0%	65.6%

List of upcoming men's college basketball games to bet on now

• Northern Iowa vs. Illinois-Chicago (5:00PM ET, Wednesday)
• Creighton vs. Xavier (6:30PM ET, Wednesday)
• St. Francis (PA) vs. Florida (6:30PM ET, Wednesday)
• Mercer vs. UCF (7:00PM ET, Wednesday)
• Vanderbilt vs. Memphis (7:00PM ET, Wednesday)
• UC Santa Barbara vs. Green Bay (7:00PM ET, Wednesday)
• Oakland vs. Northern Kentucky (7:00PM ET, Wednesday)
• Richmond vs. Elon (7:00PM ET, Wednesday)
• Youngstown State vs. Robert Morris (7:00PM ET, Wednesday)
• Quinnipiac vs. Monmouth (7:00PM ET, Wednesday)

Conclusion

Our men's college basketball best bets are locked and loaded for December 17, 2025, featuring plays such as St. Francis (PA) +45.5 and Northern Kentucky ML. Powered by advanced simulations, these picks are here to boost your betting game.

This article, enhanced by AI and automation, aims to deliver accurate college basketball insights quickly, with human oversight ensuring high editorial quality. Our predictions are sourced from current data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

All odds and probabilities in this article are correct and accurate at the time of publication.

Note: Clicking links to our sportsbook partners may earn us a referral fee. Learn about how we review products and services.