Men's college basketball picks today: Tuesday's best bets include South Carolina vs. Clemson play [12/16/2025]

South Carolina vs. Clemson over 140.5 points (-105)

• Edge: 5.1%
• Probability: 56.3%
• Matchup: South Carolina vs. Clemson (7:00PM ET, Tuesday)

Our model has identified value on over 140.5 points in South Carolina vs. Clemson at -105 odds. A 56.3% probability produces an edge of 5.1%, making this the strongest play for today's men's college basketball slate.

Evansville +9.5 (-110)

• Edge: 4.6%
• Probability: 57%
• Matchup: Belmont vs. Evansville (7:00PM ET, Tuesday)

Evansville +9.5 carries a 4.6% edge and a probability of 57% at -110 odds, according to our model.

Southern University vs. California Baptist over 153.5 points (-105)

• Edge: 4.3%
• Probability: 55.5%
• Matchup: Southern University vs. California Baptist (10:00PM ET, Tuesday)

Southern University vs. California Baptist over 153.5 points at -105 odds shows a 4.3% edge, supported by a 55.5% probability in simulations.

Abilene Christian +33.5 (-104)

• Edge: 4.0%
• Probability: 55%
• Matchup: Abilene Christian vs. Arizona (9:00PM ET, Tuesday)

A 4.0% edge and 55% probability make Abilene Christian +33.5 vs. Arizona at a value play in the Abilene Christian vs. Arizona matchup, per our model.

Towson vs. Kansas over 134.5 points (-108)

• Edge: 4.0%
• Probability: 55.9%
• Matchup: Towson vs. Kansas (9:00PM ET, Tuesday)

Towson vs. Kansas over 134.5 points at -108 odds presents a 4.0% edge, with simulations resulting in a probability of 55.9%.

California Baptist -10.5 (-110)

• Edge: 3.8%
• Probability: 56.2%
• Matchup: Southern University vs. California Baptist (10:00PM ET, Tuesday)

Our model finds value on California Baptist -10.5 at -110 odds, supported by an edge of 3.8%.

Lipscomb +33.5 (-110)

• Edge: 3.6%
• Probability: 56%
• Matchup: Lipscomb vs. Duke (6:00PM ET, Tuesday)

Our model has uncovered value on Lipscomb +33.5 at -110 odds. A 56% probability produces a 3.6% edge, making this a strong play for today's men's college basketball action.

Drexel ML (-275)

• Edge: 3.6%
• Probability: 76.9%
• Matchup: Howard vs. Drexel (11:00AM ET, Tuesday)

A 3.6% edge on a 76.9% probability makes Drexel to win at -275 odds a solid value play in today's Howard vs. Drexel matchup.

North Carolina A&T +5.5 (-120)

• Edge: 3.5%
• Probability: 58%
• Matchup: North Carolina A&T vs. UNC Greensboro (7:00PM ET, Tuesday)

Our model projects value on North Carolina A&T +5.5 at -120 odds. A 58% probability produces a 3.5% edge, making North Carolina A&T the favorable side in Saturday’s matchup.

Rider vs. Delaware over 133.5 points (-110)

• Edge: 3.4%
• Probability: 55.8%
• Matchup: Lipscomb vs. Duke (7:00PM ET, Tuesday)

Rounding out our top 10 bets, Rider vs. Delaware over 133.5 points at -110 odds shows a 55.8% probability and a 3.4% edge.

NCAAM best bets summary: Tuesday, 12/16/2025

As of 7:36AM ET, here are our top men's college basketball bets by edge recommended by our model:

Matchup	Bet	Odds	Edge	Probability
South Carolina vs. Clemson	Over 140.5 Points	-105 @ BetMGM	5.1%	56.3%
Belmont vs. Evansville	Evansville +9.5	-110 @ BetMGM	4.6%	57%
Southern University vs. California Baptist	Over 153.5 Points	-105 @ FanDuel	4.3%	55.5%
Abilene Christian vs. Arizona	Abilene Christian +33.5	-104 @ FanDuel	4.0%	55%
Towson vs. Kansas	Over 134.5 Points	-108 @ DraftKings	4.0%	55.9%
Southern University vs. California Baptist	California Baptist -10.5	-110 @ FanDuel	3.8%	56.2%
Lipscomb vs. Duke	Lipscomb +33.5	-110 @ FanDuel	3.6%	56%
Howard vs. Drexel	Drexel ML	-275 @ BetMGM	3.6%	76.9%
North Carolina A&T vs. UNC Greensboro	North Carolina A&T +5.5	-120 @ FanDuel	3.5%	58%
Rider vs. Delaware	Over 133.5 Points	-110 @ DraftKings	3.4%	55.8%

List of upcoming men's college basketball games to bet on now

• Howard vs. Drexel (11:00AM ET, Tuesday)
• Lipscomb vs. Duke (6:00PM ET, Tuesday)
• Dartmouth vs. Holy Cross (6:00PM ET, Tuesday)
• Sacred Heart vs. Massachusetts-Lowell (6:00PM ET, Tuesday)
• USC Upstate vs. South Carolina State (6:00PM ET, Tuesday)
• Toledo vs. Michigan State (6:30PM ET, Tuesday)
• Louisville vs. Tennessee (7:00PM ET, Tuesday)
• DePaul vs. St. John's (7:00PM ET, Tuesday)
• South Carolina vs. Clemson (7:00PM ET, Tuesday)
• Florida State vs. Dayton (7:00PM ET, Tuesday)

Conclusion

Our men's college basketball best bets are locked and loaded for December 16, 2025, featuring plays such as over 140.5 points in the South Carolina vs. Clemson matchup and Evansville +9.5. Powered by advanced simulations, these picks are here to boost your betting game.

This article, enhanced by AI and automation, aims to deliver accurate college basketball insights quickly, with human oversight ensuring high editorial quality. Our predictions are sourced from current data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

All odds and probabilities in this article are correct and accurate at the time of publication.

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