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Men's college basketball picks today: Tuesday's best bets highlight Southern University vs. California Baptist play [12/16/2025]

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Written by Dave Garofolo

Get college basketball picks and best bets for Tuesday, December 16, 2025.

Men's College Basketball Best Bets.
These men's college basketball betting picks for December 16, 2025, are based on the latest odds and probabilities for Tuesday's games.

Today’s men's college basketball picks for December 16, 2025 are here, with Southern University vs. California Baptist among the top plays identified by our model across Tuesday’s men's college basketball schedule.

Dimers’ predictive analytics engine runs 24/7, scanning the latest men's college basketball odds to uncover genuine betting edges. The result? Data-backed plays that help Dimers Pro members make smarter decisions.

List of NCAAM picks tonight [12/16, updated 9:32PM ET]

Below, you’ll find today’s top 10 men's college basketball bets, ranked by edge for Tuesday, December 16, 2025.

Southern University vs. California Baptist under 153.5 points (-105)

Our model has identified value on under 153.5 points in Southern University vs. California Baptist at -105 odds. A 54.7% probability produces an edge of 3.4%, making this the strongest play for today's men's college basketball slate.

 

Campbell +36.5 (-105)

A 5.8% edge and 57% probability make Campbell +36.5 vs. Gonzaga at a value play in the Campbell vs. Gonzaga matchup, per our model.

 

Vermont ML (-118)

Vermont ML at -118 odds presents a 5.5% edge, with simulations resulting in a probability of 59.6%.

 

Santa Clara ML (-475)

Our model finds value on Santa Clara to win at -475 odds, supported by an edge of 5.2%.

 

Santa Clara -10.5 (-105)

Our model has uncovered value on Santa Clara -10.5 at -105 odds. A 56.4% probability produces a 5.2% edge, making this a strong play for today's men's college basketball action.

 

Vermont -1.5 (+100)

A 4.8% edge on a 54.8% probability makes Vermont -1.5 at +100 odds a solid value play in today's Siena vs. Vermont matchup.

 

Maryland-Eastern Shore +4.5 (-105)

Our model projects value on Maryland-Eastern Shore +4.5 at -105 odds. A 55.5% probability produces a 4.3% edge, making Maryland-Eastern Shore the favorable side in Saturday’s matchup.

 

Texas Southern +33.5 (-110)

Rounding out our top 10 bets, Texas Southern +33.5 at -110 odds shows a 56% probability and a 3.6% edge.

 

NCAAM best bets summary: Tuesday, 12/16/2025

As of 9:32PM ET, here is our top men's college basketball bet by edge recommended by our model:

Matchup Bet Odds Edge Probability
Southern University vs. California Baptist Under 153.5 Points -105 @ FanDuel 3.4% 54.7%
Campbell vs. Gonzaga Campbell +36.5 -105 @ DraftKings 5.8% 57%
Siena vs. Vermont Vermont ML -118 @ BetMGM 5.5% 59.6%
North Texas vs. Santa Clara Santa Clara ML -475 @ BetMGM 5.2% 87.8%
North Texas vs. Santa Clara Santa Clara -10.5 -105 @ BetMGM 5.2% 56.4%
Siena vs. Vermont Vermont -1.5 +100 @ FanDuel 4.8% 54.8%
Maryland-Eastern Shore vs. Wagner Maryland-Eastern Shore +4.5 -105 @ DraftKings 4.3% 55.5%
Texas Southern vs. North Carolina State Texas Southern +33.5 -110 @ FanDuel 3.6% 56%

List of upcoming men's college basketball games to bet on now

Conclusion

Our men's college basketball best bets are locked and loaded for December 16, 2025, featuring plays such as under 153.5 points in the Southern University vs. California Baptist matchup. Powered by advanced simulations, these picks are here to boost your betting game.

This article, enhanced by AI and automation, aims to deliver accurate college basketball insights quickly, with human oversight ensuring high editorial quality. Our predictions are sourced from current data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

All odds and probabilities in this article are correct and accurate at the time of publication.

Note: Clicking links to our sportsbook partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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