Men's college basketball picks today: Friday's best bets include Mississippi Valley State vs. Florida State play [12/19/2025]

Mississippi Valley State +39.5 (-105)

• Edge: 8.8%
• Probability: 60%
• Matchup: Mississippi Valley State vs. Florida State (7:00PM ET, Friday)

Our model has identified value on Mississippi Valley State +39.5 at -105 odds. A 60% probability produces an edge of 8.8%, making this the strongest play for today's men's college basketball slate.

Norfolk State -6.5 (-102)

• Edge: 6.8%
• Probability: 57.3%
• Matchup: Norfolk State vs. Jackson State (7:30PM ET, Friday)

Norfolk State -6.5 carries a 6.8% edge and a probability of 57.3% at -102 odds, according to our model.

Southeastern Louisiana vs. LSU over 144.5 points (-105)

• Edge: 5.7%
• Probability: 56.9%
• Matchup: Southeastern Louisiana vs. LSU (8:00PM ET, Friday)

Southeastern Louisiana vs. LSU over 144.5 points at -105 odds shows a 5.7% edge, supported by a 56.9% probability in simulations.

Norfolk State ML (-295)

• Edge: 5.0%
• Probability: 79.7%
• Matchup: Norfolk State vs. Jackson State (7:30PM ET, Friday)

A 5.0% edge and 79.7% probability make Norfolk State at the moneyline at a value play in the Norfolk State vs. Jackson State matchup, per our model.

Alcorn State +35.5 (-104)

• Edge: 5.0%
• Probability: 56%
• Matchup: Alcorn State vs. Baylor (8:00PM ET, Friday)

Alcorn State +35.5 at -104 odds presents a 5.0% edge, with simulations resulting in a probability of 56%.

Seattle +7.5 (-110)

• Edge: 4.9%
• Probability: 57.3%
• Matchup: Washington vs. Seattle (11:30PM ET, Friday)

Our model finds value on Seattle +7.5 at -110 odds, supported by an edge of 4.9%.

Seattle ML (+300)

• Edge: 4.3%
• Probability: 29.3%
• Matchup: Washington vs. Seattle (11:30PM ET, Friday)

Our model has uncovered value on Seattle ML at +300 odds. A 29.3% probability produces a 4.3% edge, making this a strong play for today's men's college basketball action.

Villanova ML (+190)

• Edge: 3.8%
• Probability: 38.4%
• Matchup: Villanova vs. Wisconsin (8:00PM ET, Friday)

A 3.8% edge on a 38.4% probability makes Villanova to win at +190 odds a solid value play in today's Villanova vs. Wisconsin matchup.

Cal Poly vs. UCLA under 160.5 points (-108)

• Edge: 3.4%
• Probability: 55.3%
• Matchup: Cal Poly vs. UCLA (10:00PM ET, Friday)

Our model projects value on under 160.5 points at -108 odds. A 55.3% probability produces a 3.4% edge, making the under the favorable side in Saturday’s matchup.

Providence -2.5 (-110)

• Edge: 3.2%
• Probability: 55.6%
• Matchup: Washington vs. Seattle (6:30PM ET, Friday)

Rounding out our top 10 bets, Providence -2.5 at -110 odds shows a 55.6% probability and a 3.2% edge.

NCAAM best bets summary: Friday, 12/19/2025

As of 4:33AM ET, here are our top men's college basketball bets by edge recommended by our model:

Matchup	Bet	Odds	Edge	Probability
Mississippi Valley State vs. Florida State	Mississippi Valley State +39.5	-105 @ BetMGM	8.8%	60%
Norfolk State vs. Jackson State	Norfolk State -6.5	-102 @ FanDuel	6.8%	57.3%
Southeastern Louisiana vs. LSU	Over 144.5 Points	-105 @ BetMGM	5.7%	56.9%
Norfolk State vs. Jackson State	Norfolk State ML	-295 @ FanDuel	5.0%	79.7%
Alcorn State vs. Baylor	Alcorn State +35.5	-104 @ FanDuel	5.0%	56%
Washington vs. Seattle	Seattle +7.5	-110 @ BetMGM	4.9%	57.3%
Washington vs. Seattle	Seattle ML	+300 @ FanDuel	4.3%	29.3%
Villanova vs. Wisconsin	Villanova ML	+190 @ FanDuel	3.8%	38.4%
Cal Poly vs. UCLA	Under 160.5 Points	-108 @ DraftKings	3.4%	55.3%
Seton Hall vs. Providence	Providence -2.5	-110 @ FanDuel	3.2%	55.6%

List of upcoming men's college basketball games to bet on now

• Dartmouth vs. Sacred Heart (11:00AM ET, Friday)
• South Dakota State vs. Milwaukee (5:00PM ET, Friday)
• Coppin State vs. Navy (5:00PM ET, Friday)
• Hampton vs. Grambling State (5:00PM ET, Friday)
• Seton Hall vs. Providence (6:30PM ET, Friday)
• Mississippi Valley State vs. Florida State (7:00PM ET, Friday)
• Eastern Michigan vs. Akron (7:00PM ET, Friday)
• Mount St. Mary's vs. Drexel (7:00PM ET, Friday)
• La Salle vs. High Point (7:00PM ET, Friday)
• Tulsa vs. Western Kentucky (7:30PM ET, Friday)

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Conclusion

Our men's college basketball best bets are locked and loaded for December 19, 2025, featuring plays such as Mississippi Valley State +39.5 and Norfolk State -6.5. Powered by advanced simulations, these picks are here to boost your betting game.

This article, enhanced by AI and automation, aims to deliver accurate college basketball insights quickly, with human oversight ensuring high editorial quality. Our predictions are rooted in current data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

All odds and probabilities in this article are correct and accurate at the time of publication.

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