Men's college basketball picks today: Friday's best bets include Niagara vs. Siena play [12/5/2025]

Niagara vs. Siena over 130.5 points (-105)

• Edge: 5.2%
• Probability: 56.4%
• Matchup: Niagara vs. Siena (7:00PM ET, Friday)

Our model has identified value on over 130.5 points in Niagara vs. Siena at -105 odds. A 56.4% probability produces an edge of 5.2%, making this the strongest play for today's men's college basketball slate.

Bryant University +5.5 (-105)

• Edge: 4.0%
• Probability: 55.2%
• Matchup: Bryant University vs. Brown (7:00PM ET, Friday)

Bryant University +5.5 carries a 4.0% edge and a probability of 55.2% at -105 odds, according to our model.

Kentucky +5.5 (-118)

• Edge: 3.9%
• Probability: 58%
• Matchup: Gonzaga vs. Kentucky (7:00PM ET, Friday)

Kentucky +5.5 vs. Gonzaga at -118 odds shows a 3.9% edge, supported by a 58% probability in simulations.

Quinnipiac +2.5 (-108)

• Edge: 3.7%
• Probability: 55.6%
• Matchup: Quinnipiac vs. Iona (7:00PM ET, Friday)

A 3.7% edge and 55.6% probability make Quinnipiac +2.5 vs. Iona at a value play in the Quinnipiac vs. Iona matchup, per our model.

Siena -14.5 (-102)

• Edge: 2.7%
• Probability: 53.2%
• Matchup: Niagara vs. Siena (7:00PM ET, Friday)

Siena -14.5 at -102 odds presents a 2.7% edge, with simulations resulting in a probability of 53.2%.

Cincinnati vs. Xavier over 146.5 points (-105)

• Edge: 2.7%
• Probability: 53.9%
• Matchup: Cincinnati vs. Xavier (7:30PM ET, Friday)

Our model finds value on over 146.5 points in Cincinnati vs. Xavier at -105 odds, supported by an edge of 2.7%.

Marist ML (-450)

• Edge: 2.6%
• Probability: 84.4%
• Matchup: Mount St. Mary's vs. Marist (7:00PM ET, Friday) Our model has uncovered value on Marist ML at -450 odds. An 84.4% probability produces a 2.6% edge, making this a strong play for today's men's college basketball action.

Kentucky ML (+200)

• Edge: 2.5%
• Probability: 37.1%
• Matchup: Gonzaga vs. Kentucky (7:00PM ET, Friday)

A 2.5% edge on a 37.1% probability makes Kentucky to win at +200 odds a solid value play in today's Gonzaga vs. Kentucky matchup.

Marist -9.5 (-110)

• Edge: 2.4%
• Probability: 54.7%
• Matchup: Mount St. Mary's vs. Marist (7:00PM ET, Friday)

Our model projects value on Marist -9.5 at -110 odds. A 54.7% probability produces a 2.4% edge, making Marist the favorable side in Saturday’s matchup.

UAB +1.5 (-102)

• Edge: 2.1%
• Probability: 52.6%
• Matchup: UAB vs. Drake (7:30PM ET, Friday)

Rounding out our top 10 bets, UAB +1.5 at -102 odds shows a 52.6% probability and a 2.1% edge.

NCAAM best bets summary: Friday, 12/5/2025

As of 2:31AM ET, here are our top men's college basketball bets by edge recommended by our model:

Matchup	Bet	Odds	Edge	Probability
Niagara vs. Siena	Over 130.5 Points	-105 @ FanDuel	5.2%	56.4%
Bryant University vs. Brown	Bryant University +5.5	-105 @ BetMGM	4.0%	55.2%
Gonzaga vs. Kentucky	Kentucky +5.5	-118 @ FanDuel	3.9%	58%
Quinnipiac vs. Iona	Quinnipiac +2.5	-108 @ DraftKings	3.7%	55.6%
Niagara vs. Siena	Siena -14.5	-102 @ DraftKings	2.7%	53.2%
Cincinnati vs. Xavier	Over 146.5 Points	-105 @ FanDuel	2.7%	53.9%
Mount St. Mary's vs. Marist	Marist ML	-450 @ BetMGM	2.6%	84.4%
Gonzaga vs. Kentucky	Kentucky ML	+200 @ DraftKings	2.5%	37.1%
Mount St. Mary's vs. Marist	Marist -9.5	-110 @ BetMGM	2.4%	54.7%
UAB vs. Drake	UAB +1.5	-102 @ DraftKings	2.1%	52.6%

List of upcoming men's college basketball games to bet on now

• Niagara vs. Siena (7:00PM ET, Friday)
• Mount St. Mary's vs. Marist (7:00PM ET, Friday)
• Quinnipiac vs. Iona (7:00PM ET, Friday)
• South Alabama vs. East Tennessee State (7:00PM ET, Friday)
• Gonzaga vs. Kentucky (7:00PM ET, Friday)
• Canisius vs. St. Peter's (7:00PM ET, Friday)
• Fairfield vs. Manhattan (7:00PM ET, Friday)
• Samford vs. Virginia Commonwealth (7:00PM ET, Friday)
• Bryant University vs. Brown (7:00PM ET, Friday)
• South Carolina State vs. Bethune-Cookman (7:00PM ET, Friday)

Conclusion

Our men's college basketball best bets are locked and loaded for December 5, 2025, featuring plays such as over 130.5 points in the Niagara vs. Siena matchup and Bryant University +5.5. Powered by advanced simulations, these picks are here to boost your betting game.

This article, enhanced by AI and automation, aims to deliver accurate college basketball insights quickly, with human oversight ensuring high editorial quality. Our predictions are based on current data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

All odds and probabilities in this article are correct and accurate at the time of publication.

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