Grizzlies vs. Mavericks prediction: Memphis favored to win Saturday's NBA matchup [11/22/2025]

NBA action continues on Saturday at 8:30PM ET as the Memphis Grizzlies square off with the Dallas Mavericks at American Airlines Center.

Based on the latest simulation results and today’s injury updates, Dimers' advanced NBA model gives the Grizzlies a slight edge with a 54% win probability over the Mavericks.

This prediction follows the latest NBA Injury Report, which suggests the Mavericks lineup will feature players like P.J. Washington, Brandon Williams and Cooper Flagg, while the Grizzlies will rely on Santi Aldama, Cedric Coward and Zach Edey.

This article offers a closer look at Saturday's Grizzlies vs. Mavericks matchup, including an expanded look at the predicted score, best bets and player prop picks.

Grizzlies vs. Mavs prediction: Who will win and cover?

As part of Dimers' NBA predictions coverage—and following a review of recent results—our pregame model has generated moneyline, spread, and over/under probabilities for Saturday's clash between the Grizzlies and Mavericks.

Our famous predictive model currently gives the Grizzlies a 54% chance of defeating the Mavericks. Our predicted final score has the Grizzlies winning 115-114.

According to our model, the Mavericks (-1.5) have a 55% chance of covering the spread, while the over/under total of 230.5 points has a 52% chance of staying under.

Grizzlies vs. Mavericks odds

We have sourced the best NBA odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Grizzlies vs. Mavericks picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

According to our best NBA bets for Saturday, the top play to make on this game is Mavericks -1.5 at the spread.

Grizzlies vs. Mavericks player props

Looking for Memphis vs. Dallas NBA prop bets? We have crunched the numbers to project how each team's leading players will perform at American Airlines Center.

Santi Aldama is expected to lead the Grizzlies with 16 points, 6 rebounds and 4 assists, while P.J. Washington is projected to have 17 points, 8 rebounds and 3 assists for the Mavericks.

Check out our NBA player projections for a full range of projected box scores, including points, assists, rebounds and more, for every game this season.

Grizzlies prediction

Our model's projected player stats for the Grizzlies are:

Mavericks prediction

Projected points, rebounds, assists and three-pointers made for the Mavericks:

Grizzlies vs. Mavs game-day updates and essential details

Saturday's game between the Mavericks and Grizzlies at American Airlines Center is scheduled to begin at 8:30PM ET.

• Who: Memphis Grizzlies vs. Dallas Mavericks
• Date: Saturday, November 22, 2025
• Time: 8:30PM ET/5:30PM PT
• Venue: American Airlines Center

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Conclusion

We predict the Grizzlies, with a 54% win probability, will likely beat the Mavericks on Saturday, with P.J. Washington projected for a game-high 38 fantasy points.

AI and automation have enhanced this article to quickly deliver accurate Grizzlies vs. Mavericks insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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