Massachusetts-Lowell vs. Boston University prediction: Boston University favored to win men's college basketball matchup [12/21/2025]

Boston University and Massachusetts-Lowell will lock horns in men's college basketball action at Case Gym on Sunday, starting at 12:00 PM ET.

Based on the latest simulation results, Dimers' advanced college basketball model predicts Boston University as the most likely winner of the Massachusetts-Lowell vs. Boston University game.

This article offers further insights into Sunday's matchup, including an expanded look at the predicted score, best bets and picks.

Massachusetts-Lowell vs. Boston University prediction: Who will win and cover?

Using powerful machine learning and statistical analysis, we have simulated the outcome of Sunday's NCAA basketball game between Massachusetts-Lowell and Boston University 10,000 times as part of our men's college basketball predictions coverage.

Our famous predictive model currently gives Boston University a 58% chance of beating Massachusetts-Lowell. Our predicted final score has Boston University winning 72-70.

According to our model, Massachusetts-Lowell (+3.5) has a 58% chance of covering the spread, while the 145.5-point over/under has a 54% chance of staying under.

Massachusetts-Lowell vs. Boston University odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Massachusetts-Lowell vs. Boston University picks and best bet

After matching our probabilities against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: