Maryland-Eastern Shore vs. American University prediction: Why American University is favored to win men's college basketball matchup [12/6/2025]

American University and Maryland-Eastern Shore will meet in men's college basketball action at Bender Arena on Saturday, with tipoff at 2:00PM ET.

Based on updated simulation results, Dimers' proven college basketball model predicts American University as the most likely winner of the Maryland-Eastern Shore vs. American University game.

This article offers further insights into Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

Maryland-Eastern Shore vs. American University prediction: Who will win and cover?

Using powerful machine learning and data, we have simulated the outcome of Saturday's NCAA basketball matchup between Maryland-Eastern Shore and American University 10,000 times as part of our men's college basketball predictions coverage.

Our leading predictive model gives American University a 90% chance of beating Maryland-Eastern Shore. Our predicted final score has American University winning 72-60.

According to our model, American University (-11.5) has a 54% chance of covering the spread, while the over/under total of 129.5 points has a 54% chance of going over.

Maryland-Eastern Shore vs. American University odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Maryland-Eastern Shore vs. American University picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: