Mariners vs. Red Sox Prediction and Odds - May 22, 2022

The Boston Red Sox take on the Seattle Mariners at Fenway Park on Sunday, starting at 1:35PM ET.

Nathan Eovaldi (1-2, 4.32 ERA) will start on the mound for the Red Sox, while the Mariners are going with Logan Gilbert (4-2, 2.40 ERA).

Dimers' top betting picks for Mariners vs. Red Sox, plus game predictions and best odds, are featured in this article.

This Seattle vs. Boston betting analysis is presented by PointsBet, which has a great 5x $100 Risk-Free Bets offer for new users.

Who will win Mariners vs. Red Sox?

Using advanced computer power and data, Dimers.com has simulated Sunday's Mariners-Red Sox MLB matchup 10,000 times.

Dimers' independent predictive analytics model, DimersBOT, gives the Red Sox a 56% chance of winning against the Mariners .

More: Full Betting Analysis for Mariners vs. Red Sox

Mariners vs. Red Sox Game Odds

• Run Line: Red Sox -1.5 (+150), Mariners +1.5 (-165)
• Moneyline: Red Sox -130, Mariners +114
• Total: Over/Under 9.5 (+100/-105)

Run Line, Moneyline and Over/Under

The Red Sox are currently -1.5 favorites against the Mariners, with +150 at DraftKings Sportsbook the best odds currently available.

For the underdog Mariners (+1.5) to cover the run line, BetMGM has the best odds currently on offer at -165.

Caesars Sportsbook currently has the best moneyline odds for the Red Sox at -130. That means you can risk $130 to win $100, for a total payout of $230, if they get the W.

On the other hand, FanDuel Sportsbook currently has the best moneyline odds for the Mariners at +114, where you can bet $100 to profit $114, earning a total payout of $214, if they win.

The Over/Under for total runs scored is set at 9.5 with Caesars Sportsbook, which currently has the best odds for the Over at +100, while PointsBet currently has the best odds for the Under at -105.

As always, make sure you check all the online sportsbooks that are available in your state for the best MLB odds and lines.

According to DimersBOT, the Mariners (+1.5) are a 60% chance of covering the run line, while the 9.5-run Over/Under is a 52% chance of going Under.

More: Today's Best Bets for All Major Sports

Best Bets for Mariners vs. Red Sox

• Run Line: Red Sox -1.5 @ +150 via DraftKings Sportsbook
• Moneyline: Red Sox @ -130 via Caesars Sportsbook (56% probability)
• Total: Under 9.5 @ -105 via PointsBet (52% probability)

Dimers' best bets are based on complex simulations and wagering intelligence to serve you the best possible plays 24/7/365.

Although the Mariners are more likely to cover the run line, our best bet of Red Sox -1.5 is based on the chance of that happening, according to DimersBOT, and the top odds available.

Mariners vs. Red Sox Probabilities

Use our interactive widget below to explore up-to-date Moneyline, Over/Under and Run Line probabilities and odds for Seattle vs. Boston, and click or tap on See Matchup for more.

Dimers has full betting coverage of Sunday's Mariners-Red Sox matchup, including pregame predictions, free picks, and live win probabilities.

Don't forget, DimersBOT updates frequently, so keep an eye on this article for any changes to our betting insights before Mariners vs. Red Sox on Sunday May 22, 2022.

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Mariners vs. Red Sox 2022 Game Info

Sunday's game between the Red Sox and Mariners at Fenway Park is scheduled to begin at 1:35PM ET.

• Date: Sunday May 22, 2022
• Time: 1:35PM ET / 10:35AM PT
• Venue: Fenway Park

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What MLB games are on today?

Now you've got the 411 on Mariners vs. Red Sox, check out the latest betting analysis for all upcoming MLB games in our MLB Bet Hub. There you can find probabilities and odds, plus our best bets for each and every MLB matchup.

Want a pick for the Run Line? You got it. How about the Over/Under? Yup, got that too. The Moneyline? Yes sir. And these picks are good, I mean REALLY good. Take a look now!

Lastly, Dimers' MLB Futures page is our in-house approach to determining who will win the 2022 World Series, with our data-led probabilities matched against the best odds to win the World Series.