Mariners vs. Astros Prediction and Odds - May 3, 2022

The Houston Astros and Seattle Mariners are scheduled to meet in MLB at Minute Maid Park on Tuesday, starting at 8:10PM ET.

The Astros will have Cristian Javier (1-0, 1.35 ERA) start, while the Mariners will counter with Chris Flexen (1-3, 3.38 ERA).

Dimers' best betting picks for Mariners vs. Astros, plus game predictions and best odds, are detailed in this article.

This Seattle vs. Houston betting preview is presented by PointsBet, which has a 5x $100 Risk-Free Bets promo for new users.

Who will win Mariners vs. Astros?

Using trusted computer power and data, Dimers.com has simulated Tuesday's Mariners-Astros MLB game 10,000 times.

Dimers' renowned predictive analytics model, DimersBOT, currently gives the Astros a 63% chance of winning against the Mariners.

More: Free Betting Guide for Mariners vs. Astros

Mariners vs. Astros Game Odds

• Run Line: Astros -1.5 (+130), Mariners +1.5 (-145)
• Moneyline: Astros -155, Mariners +140
• Total: Over/Under 8.5 (-105/-110)

Run Line, Moneyline and Over/Under

The Astros are -1.5 favorites against the Mariners, with +130 at DraftKings Sportsbook the best odds currently available.

For the underdog Mariners (+1.5) to cover the run line, BetMGM has the best odds currently on the market at -145.

DraftKings Sportsbook currently has the best moneyline odds for the Astros at -155, which means you can risk $155 to win $100, for a total payout of $255, if they get the W.

Meanwhile, FanDuel Sportsbook currently has the best moneyline odds for the Mariners at +140, where you can put down $100 to profit $140, earning a total payout of $240, if they win.

The Over/Under for total runs scored sits at 8.5 with DraftKings Sportsbook, which currently has the best odds for the Over at -105, while Caesars Sportsbook currently has the best odds for the Under at -110.

As always, make sure you check all the online sportsbooks that are available in your state for the best MLB odds and lines.

According to DimersBOT, the Mariners (+1.5) are a 55% chance of covering the run line, while the Over/Under total of 8.5 runs is a 52% chance of going Over.

More: Live Win Probabilities for All Major Sports

Best Bets for Mariners vs. Astros

• Run Line: Astros -1.5 @ +130 via DraftKings Sportsbook (1.5% edge)
• Moneyline: Astros @ -155 via DraftKings Sportsbook (63% probability)
• Total: Over 8.5 @ -105 via DraftKings Sportsbook (52% probability)

Dimers' best bets are based on complex simulations and wagering intelligence to serve you the best possible plays 24/7.

Although the Mariners are more likely to cover the run line, our best bet of Astros -1.5 is based on the expectation of that happening, according to DimersBOT, and the top odds available.

Mariners vs. Astros Betting Guide

Use our dynamic widget below to view up-to-date Moneyline, Over/Under and Run Line probabilities and odds for Seattle vs. Houston, and click or tap on See Matchup to reveal more.

Dimers has full coverage of Tuesday's Mariners-Astros matchup, including pregame predictions, free betting picks, and live win probabilities.

Remember, DimersBOT updates regularly, so refresh this page for any changes to our betting insights before Mariners vs. Astros on Tuesday May 3, 2022.

Best Sportsbook Offer for Mariners vs. Astros

Do you want to bet on Seattle vs. Houston? Join FanDuel Sportsbook now and get your first bet risk free up to $1,000, which you can use on Tuesday's Mariners-Astros game.

Simply click or tap on this exclusive FanDuel Sportsbook link and create an account – it's easy and takes less than 2 minutes.

Then, make your first deposit and place a bet up to $1,000 on Mariners vs. Astros. If you don't win your bet, FanDuel Sportsbook will refund it in site credit!

This offer is available to all new FanDuel Sportsbook users. How good is that!

Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.

Mariners vs. Astros 2022 Game Info

When do the Astros play the Mariners?

• Date: Tuesday May 3, 2022
• Time: 8:10PM ET / 5:10PM PT
• Venue: Minute Maid Park

Ready to join an online sportsbook and start betting on MLB today? Check out the best sportsbook offers in your state.

Want more MLB analysis like this?

So, you liked our Mariners vs. Astros betting analysis? Awesome. Did you know our MLB Betting News section has a comprehensive betting preview for every MLB game the second the sportsbooks put out their odds?

That's right, our predictive analytics model then compares those odds against its own probabilities to find value in the markets, which allows us to write the most authoritative MLB betting previews and get the jump on the public and the sportsbooks.

It's only a click away, so why not see for yourself?

Lastly, Dimers' Baseball Futures page is our in-house approach to revealing who will win the 2022 World Series, with our data-led probabilities paired with the best odds on the market.