Mariners vs. Astros Prediction and Odds - May 2, 2022

The Houston Astros square off with the Seattle Mariners in MLB action at Minute Maid Park on Monday, starting at 8:10PM ET.

The Astros will send Jake Odorizzi (1-2, 6.00 ERA) to the mound, while the Mariners are going with Marco Gonzales (1-2, 3.86 ERA).

Dimers' best betting picks for Mariners vs. Astros, as well as game predictions and best odds, are featured in this article.

Today's Seattle vs. Houston betting preview is brought to you by PointsBet, which has a 5x $100 Risk-Free Bets promo for new customers.

Who will win Mariners vs. Astros?

Based on high-tech machine learning and data, Dimers.com has simulated Monday's Mariners-Astros MLB matchup 10,000 times.

Dimers' popular predictive analytics model, DimersBOT, gives the Astros a 57% chance of defeating the Mariners.

More: Mariners vs. Astros Simulated 10,000 Times

Mariners vs. Astros Game Odds

• Run Line: Astros -1.5 (+145), Mariners +1.5 (-162)
• Moneyline: Astros -135, Mariners +126
• Total: Over/Under 9 (+100/-115)

Run Line, Moneyline and Over/Under

The Astros are -1.5 favorites versus the Mariners, with +145 at DraftKings Sportsbook the best odds currently available.

For the underdog Mariners (+1.5) to cover the run line, FanDuel Sportsbook has the best odds currently on offer at -162.

DraftKings Sportsbook currently has the best moneyline odds for the Astros at -135. That means you can risk $135 to win $100, for a total payout of $235, if they get the W.

Meanwhile, FanDuel Sportsbook currently has the best moneyline odds for the Mariners at +126, where you can put down $100 to profit $126, earning a total payout of $226, if they win.

The Over/Under for total runs scored sits at 9 with BetMGM, which currently has the best odds for the Over at +100, while DraftKings Sportsbook currently has the best odds for the Under at -115.

As always, make sure you check the sportsbooks you can bet with in your state for the best MLB odds and lines.

According to DimersBOT, the Mariners (+1.5) are a 60% chance of covering the run line, while the Over/Under total of 9 runs is considered an equal 50-50 chance of hitting.

More: Best Bets for Every MLB Game

Best Bets for Mariners vs. Astros

• Run Line: Astros -1.5 @ +145 via DraftKings Sportsbook
• Moneyline: Astros @ -135 via DraftKings Sportsbook (57% probability)
• Total: Over 9 @ +100 via BetMGM (50% probability)

Dimers' best bets are based on complex simulations and betting intelligence to help you make smarter decisions with the legal sportsbooks in your state.

Even though the Mariners are more likely to cover the run line, our best bet of Astros -1.5 is based on the chance of that happening, according to DimersBOT, and the best odds available.

Mariners vs. Astros Probabilities

Use our widget below to explore up-to-date Moneyline, Over/Under and Run Line probabilities and odds for Seattle vs. Houston, and click or tap on See Matchup for more.

Dimers has full betting coverage of Monday's Mariners-Astros matchup, including pregame predictions, computer picks, and live win probabilities.

Don't forget, DimersBOT updates frequently, so check this page for any changes to our betting insights before Mariners vs. Astros on Monday May 2, 2022.

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Mariners vs. Astros 2022 Game Info

When do the Astros play the Mariners?

• Date: Monday May 2, 2022
• Time: 8:10PM ET / 5:10PM PT
• Venue: Minute Maid Park

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Want more MLB predictions like this?

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That's right, our predictive analytics model then compares those odds against its own probabilities to find edges in the markets. This allows us to write the most reliable MLB betting previews and beat the public and the sportsbooks to the punch.

It's only a click away, so why not take a look around?

Finally, Dimers' Baseball Futures page is our in-house approach to revealing who will win the 2022 World Series, with our data-led probabilities matched against the best odds to win the World Series.