MLB- More Betting
Mariners vs. Astros Prediction and Odds - Jun 8, 2022

The Houston Astros face the Seattle Mariners in MLB action at Minute Maid Park on Wednesday, starting at 6:40PM ET.
José Urquidy (5-2, 4.76 ERA) will start on the mound for the Astros, while the Mariners are going with Logan Gilbert (5-2, 2.22 ERA).
Dimers' free betting picks for Mariners vs. Astros, plus game predictions and best odds, are detailed below.
Who will win Mariners vs. Astros?
Based on cutting-edge computer power and data, Dimers.com has simulated Wednesday's Mariners-Astros MLB matchup 10,000 times.
Dimers' proven predictive analytics model, DimersBOT, currently gives the Astros a 55% chance of defeating the Mariners.
More: Mariners vs. Astros Simulated 10K Times
Mariners vs. Astros Game Odds
- Run Line: Astros -1.5 (+150), Mariners +1.5 (-161)
- Moneyline: Astros -135, Mariners +120
- Total: Over/Under 8.5 (+100/-115)
Run Line, Moneyline and Over/Under
The Astros are -1.5 favorites versus the Mariners, with +150 at DraftKings Sportsbook the best odds currently available.
For the underdog Mariners (+1.5) to cover the run line, Caesars Sportsbook has the best odds currently on offer at -161.
DraftKings Sportsbook currently has the best moneyline odds for the Astros at -135. That means you can risk $135 to win $100, for a total payout of $235, if they get the W.
Meanwhile, BetMGM currently has the best moneyline odds for the Mariners at +120, where you can bet $100 to profit $120, earning a total payout of $220, if they win.
The Over/Under for total runs scored sits at 8.5 with PointsBet, which currently has the best odds for the Over at +100, while Caesars Sportsbook currently has the best odds for the Under at -115.
As always, make sure you check all the sportsbooks that are available in your state for the best MLB odds and lines.
According to DimersBOT, the Mariners (+1.5) are a 62% chance of covering the run line, while the Over/Under total of 8.5 runs is a 51% chance of going Over.
More: Track Your Bets via Bet Center
Best Bets for Mariners vs. Astros
- Run Line: Mariners +1.5 @ -161 via Caesars Sportsbook (62% probability)
- Moneyline: Mariners @ +120 via BetMGM
- Total: Over 8.5 @ +100 via PointsBet (51% probability)
Dimers' best bets are based on complex simulations and betting intelligence to help you make more informed decisions with the legal sportsbooks in America.
While the Astros are more likely to win the game, according to DimersBOT, betting on the Mariners moneyline is the best option due to the edge found when comparing our data-led probabilities to the sportsbooks' odds currently available.
Taking advantage of the edges seen here at Dimers is crucial to being a profitable bettor in the long run.
Mariners vs. Astros Betting Guide
Use our interactive widget below to explore up-to-date Moneyline, Over/Under and Run Line probabilities and odds for Seattle vs. Houston, and click or tap on See Matchup to reveal more.
Dimers has full coverage of Wednesday's Mariners-Astros matchup, including pregame predictions, best betting picks, and live win probabilities.
Remember, DimersBOT updates regularly, so refresh this article for any changes to our betting analysis before Mariners vs. Astros on Wednesday June 8, 2022.
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Mariners vs. Astros 2022 Game Info
Wednesday's action between the Astros and Mariners at Minute Maid Park is scheduled to start at 6:40PM ET.
- Who: Houston Astros vs. Seattle Mariners
- Date: Wednesday June 8, 2022
- Time: 6:40PM ET / 3:40PM PT
- Venue: Minute Maid Park
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