Mariners vs. Astros Prediction and Odds - Jul 28, 2022

The Houston Astros and Seattle Mariners are scheduled to meet in MLB at Minute Maid Park on Thursday, starting at 8:10PM ET.

José Urquidy (9-4, 3.93 ERA) will get the ball for the Astros, while the Mariners are going with Logan Gilbert (10-4, 2.77 ERA).

Dimers' top betting picks for Mariners vs. Astros, as well as game predictions and best odds, are detailed in this article.

Who will win Mariners vs. Astros?

Using state-of-the-art machine learning and data, Dimers.com has simulated Thursday's Mariners-Astros MLB matchup 10,000 times.

Dimers' famous predictive analytics model, DimersBOT, currently gives the Astros a 61% chance of winning against the Mariners.

More: Mariners vs. Astros Simulated 10K Times

Mariners vs. Astros Odds

• Run Line: Astros -1.5 (+145), Mariners +1.5 (-165)
• Moneyline: Astros -135, Mariners +120
• Total: Over/Under 8.5 (+100/-120)

Run Line, Moneyline and Over/Under

The Astros are currently -1.5 favorites versus the Mariners, with +145 at BetMGM the best odds currently available.

For the underdog Mariners (+1.5) to cover the run line, DraftKings Sportsbook has the best odds currently on the market at -165.

DraftKings Sportsbook currently has the best moneyline odds for the Astros at -135. That means you can risk $135 to win $100, for a total payout of $235, if they get the W.

Elsewhere, FanDuel Sportsbook currently has the best moneyline odds for the Mariners at +120, where you can bet $100 to profit $120, earning a total payout of $220, if they win.

The Over/Under for total runs scored is set at 8.5 with DraftKings Sportsbook, which currently has the best odds for the Over at +100, as well as the best odds for the Under at -120.

As always, check out the sportsbooks you can bet with in your state for the best MLB odds and lines.

According to DimersBOT, the Mariners (+1.5) are a 58% chance of covering the run line, while the 8.5-run Over/Under is a 51% chance of going Over.

More: Live Win Probabilities for All Major Sports

Best Bets for Mariners vs. Astros

• Run Line: Astros -1.5 @ +145 via BetMGM (1.3% edge)
• Moneyline: Astros @ -135 via DraftKings Sportsbook (61% probability)
• Total: Over 8.5 @ +100 via DraftKings Sportsbook (51% probability)

Our best bets are based on complex simulations and betting intelligence to bring you the best possible plays 24/7/365.

Although the Mariners are more likely to cover the run line, our best bet of Astros -1.5 is based on the likelihood of that happening, according to DimersBOT, and the best odds available.

Mariners vs. Astros Prediction

Use our dynamic widget below to view the latest Moneyline, Over/Under and Run Line probabilities and odds for Seattle vs. Houston, and click or tap on See Matchup for more.

Dimers has full coverage of Thursday's Mariners-Astros matchup, including pregame predictions, top betting picks, and live win probabilities.

Remember, DimersBOT updates often, so keep an eye on this article for the latest betting insights ahead of Mariners vs. Astros on Thursday July 28, 2022.

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Note: When you click or tap on a link on Dimers that goes to a third-party website that we have a commercial relationship with (such as a sportsbook), we may receive a referral fee.

Mariners vs. Astros 2022 Game Info

Thursday's matchup between the Astros and Mariners at Minute Maid Park is scheduled to commence at 8:10PM ET.

• Who: Houston Astros vs. Seattle Mariners
• Date: Thursday July 28, 2022
• Time: 8:10PM ET / 5:10PM PT
• Venue: Minute Maid Park

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Want more MLB previews like this?

So, you liked our Mariners vs. Astros betting predictions? Awesome. Did you know our MLB Betting News section has a detailed betting preview for every MLB matchup the second the sportsbooks release their odds?

That's right, our predictive analytics model then compares those odds against its own probabilities to find value in the markets. This allows us to create the most authoritative MLB betting previews and get the jump on the public and the sportsbooks.

It's only a click away, so why not see for yourself?

Lastly, Dimers' MLB Futures page is our in-house approach to revealing who will win the 2022 World Series, with our data-led probabilities paired with the best odds to win the World Series.