Loyola Chicago vs. Rhode Island prediction: Why Rhode Island is favored to win men's college basketball matchup [12/31/2025]

Men's college basketball action continues on Wednesday at 12:00 PM ET as Loyola Chicago takes on Rhode Island in men's college basketball action at Thomas M. Ryan Center.

Based on the latest simulation results, Dimers' proven college basketball model predicts Rhode Island as the most likely winner of the Loyola Chicago vs. Rhode Island game.

This article offers further insights into Wednesday's matchup, including an expanded look at the predicted score, best bets and picks.

Loyola Chicago vs. Rhode Island prediction: Who will win and cover?

Using trusted machine learning and data, we have simulated the outcome of Wednesday's NCAA basketball game between Loyola Chicago and Rhode Island 10,000 times as part of our men's college basketball predictions coverage.

Our leading predictive model currently gives Rhode Island an 82% chance of beating Loyola Chicago. Our predicted final score has Rhode Island winning 77-68.

According to our model, Rhode Island (-8.5) has a 57% chance of covering the spread, while the 145.5-point over/under has a 52% chance of going over.

Loyola Chicago vs. Rhode Island odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Loyola Chicago vs. Rhode Island picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

According to our men's college basketball best bets, the top play to make on this game is Rhode Island -8.5 at the spread.

Loyola Chicago vs. Rhode Island game-day updates and essential details

Wednesday's men's college basketball action between Rhode Island and Loyola Chicago at Thomas M. Ryan Center is scheduled to begin at 12:00 PM ET.

• Who: Loyola Chicago vs. Rhode Island
• Date: Wednesday, December 31, 2025
• Time: 12:00 PM ET/9:00AM PT
• Venue: Thomas M. Ryan Center

Conclusion

We predict Rhode Island, with an 82% win probability, will likely beat Loyola Chicago on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Loyola Chicago vs. Rhode Island insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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