Loyola Chicago vs. Rhode Island prediction: Why Rhode Island is favored to win men's college basketball matchup [12/31/2025]

Rhode Island will face Loyola Chicago in men's college basketball action at Thomas M. Ryan Center on Wednesday, commencing at 12:00 PM ET.

Based on the latest simulation results, Dimers' advanced college basketball model predicts Rhode Island as the most likely winner of the Loyola Chicago vs. Rhode Island game.

This article offers an expanded analysis of Wednesday's matchup, including an expanded look at the predicted score, best bets and picks.

Loyola Chicago vs. Rhode Island prediction: Who will win and cover?

Using innovative machine learning and data, we have simulated the outcome of Wednesday's NCAA basketball matchup between Loyola Chicago and Rhode Island 10,000 times as part of our men's college basketball predictions coverage.

Our famous predictive model currently gives Rhode Island an 85% chance of defeating Loyola Chicago. Our predicted final score has Rhode Island winning 78-67.

According to our model, Rhode Island (-9.5) has a 57% chance of covering the spread, while the 147.5-point over/under has a 52% chance of staying under.

Loyola Chicago vs. Rhode Island odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Loyola Chicago vs. Rhode Island picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: