Loyola Chicago vs. DePaul CBB Predictions and Odds - Dec 4, 2021

College Basketball action continues on Saturday at 4:00 PM EST as Loyola Chicago locks horns with DePaul at Wintrust Arena.

Dimers' free betting picks for Loyola Chicago vs. DePaul, as well as game predictions and best odds, are featured below.

Who will win Loyola Chicago vs. DePaul?

Based on state-of-the-art computer power and data, Dimers.com has simulated Saturday's Loyola Chicago-DePaul NCAA Basketball game 10,000 times.

Dimers' renowned predictive analytics model, DimersBOT, gives Loyola Chicago a 62% chance of getting the W against DePaul.

MORE: Loyola Chicago vs. DePaul Simulated 10,000 Times

Point Spread, Moneyline and Over/Under

DePaul is listed as the +4.5 underdog versus Loyola Chicago, with -110 at BetMGM the best odds available.

For the favored Loyola Chicago (-4.5) to cover the spread, FanDuel Sportsbook has the best odds on offer at -102.

FanDuel Sportsbook has the best moneyline odds for DePaul at +172. That means you can bet $100 to profit $172, earning a total payout of $272, if it wins.

Elsewhere, BetMGM has the best moneyline odds for Loyola Chicago at -182, where you can risk $182 to win $100, for a total payout of $282, if it comes out on top.

The Over/Under for total points scored sits at 144.5 with BetMGM, which has the best odds for the Over at -110, as well as the best odds for the Under at -110.

As always, make sure you check the sportsbooks you can bet with in your state for the best College Basketball odds and lines.

According to DimersBOT, DePaul (+4.5) is a 61% chance of covering the spread, while the 144.5-point Over/Under is a 55% chance of going Under.

MORE: Today's Best Bets for All Major College Sports

Best Bets for Loyola Chicago vs. DePaul

• Spread: DePaul +4.5 at -110 with BetMGM (61% probability) 🔥
• Moneyline: DePaul Win at +172 with FanDuel Sportsbook (2.8% edge)
• Over/Under: Under 144.5 at -110 with BetMGM (55% probability)

Any time you see a 🔥, that means you've found one of Dimers' best free picks today across all major pro and college sports.

While Loyola Chicago is more likely to win the game, according to DimersBOT, betting on DePaul moneyline is the best option because of the 2.8% edge identified when comparing our data-led probabilities to the sportsbooks' odds.

Taking advantage of the edges published on Dimers.com is crucial to achieving long-term profitability.

Loyola Chicago vs. DePaul Score Prediction

Dimers.com's predicted final score for Loyola Chicago vs. DePaul at Wintrust Arena this Saturday has Loyola Chicago winning 73-70.

Use our dynamic widget below to explore the latest Spread, Over/Under and Moneyline probabilities and odds for the game, and click or tap on See Matchup to reveal more.

Dimers has full betting coverage of Saturday's Loyola Chicago-DePaul matchup, including pre-game predictions, free picks, and live scores.

Don't forget, DimersBOT updates frequently, so keep an eye on this page for any changes to our betting insights ahead of Loyola Chicago vs. DePaul on Saturday December 4, 2021.

Loyola Chicago vs. DePaul 2021 CBB Game Info

When does DePaul play Loyola Chicago in College Basketball?

• Date: Saturday December 4, 2021
• Time: 4:00 PM EST / 1:00 PM PST
• Venue: Wintrust Arena

Enjoy Dimers and want to keep the site free? Every time you join a sportsbook featured here, we get paid a small fee.

These fees help us keep Dimers free for all sports fans. So, if you like what you see, support us by joining one of our featured sports betting partners today.

What other CBB games are on today?

Now you've got the 411 on Loyola Chicago vs. DePaul, see the latest betting analysis for all upcoming NCAA Basketball games in Dimers' College Basketball Bet Hub. There you can find probabilities and odds, plus our best bets for every single CBB matchup.

Want a pick for the Spread? You got it. How about the Over/Under? Yup, got that too. The Moneyline? Yes sir. And these picks are good, I mean REALLY good. Take a look now!