Louisville vs. Notre Dame CBB Predictions and Odds - Feb 9, 2022

Notre Dame takes on Louisville in College Basketball action at Purcell Pavilion on Wednesday, starting at 7:00PM EST.

Dimers' top betting picks for Louisville vs. Notre Dame, as well as game predictions and best odds, are detailed in this article.

Who will win Louisville vs. Notre Dame?

Using cutting-edge machine learning and data, Dimers.com has simulated Wednesday's Louisville-Notre Dame NCAA Basketball game 10,000 times.

Dimers' popular predictive analytics model, DimersBOT, currently gives Notre Dame a 73% chance of defeating Louisville.

MORE: Louisville vs. Notre Dame Simulated 10K Times

Point Spread, Moneyline and Over/Under

Notre Dame is the -7.5 favorite against Louisville, with +100 at DraftKings Sportsbook the best odds currently available.

For the underdog Louisville (+7.5) to cover the spread, DraftKings Sportsbook also has the best odds currently on the market at -120.

FanDuel Sportsbook currently has the best moneyline odds for Notre Dame at -275, which means you can risk $275 to win $100, for a total payout of $375, if it gets the W.

Elsewhere, BetMGM currently has the best moneyline odds for Louisville at +260, where you can bet $100 to profit $260, earning a total payout of $360, if it wins.

The Over/Under for total points scored sits at 133.5 with PointsBet, which currently has the best odds for the Over at -110, as well as the best odds for the Under at -110.

As always, check out all the sportsbooks available in your state for the best College Basketball odds and lines.

According to DimersBOT, Louisville (+7.5) is a 66% chance of covering the spread, while the 133.5-point Over/Under is a 53% chance of going Over.

MORE: Predictions for Every College Basketball Game

Best Bets for Louisville vs. Notre Dame

• Spread: Louisville +7.5 at -120 with DraftKings Sportsbook (66% probability) 🔥
• Moneyline: Notre Dame at -275 with FanDuel Sportsbook (73% probability)
• Over/Under: Over 133.5 at -110 with PointsBet (53% probability)

If you see a 🔥, that means you've found one of our best bets of the day across all sports.

Dimers' best bets are based on detailed simulations and wagering intelligence to help you make more informed investments.

Louisville vs. Notre Dame Score Prediction

Dimers.com's predicted final score for Louisville vs. Notre Dame at Purcell Pavilion this Wednesday has Notre Dame winning 70-64.

Use our dynamic widget below to explore the latest Spread, Over/Under and Moneyline probabilities and odds for the game, and click or tap on See Matchup to reveal more.

Dimers has full coverage of Wednesday's Louisville-Notre Dame matchup, including pre-game predictions, computer picks, and live scores.

Remember, DimersBOT updates regularly, so keep an eye on this article for any changes to our betting analysis before Louisville vs. Notre Dame on Wednesday February 9, 2022.

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Louisville vs. Notre Dame 2022 CBB Game Info

When does Notre Dame play Louisville in College Basketball?

• Date: Wednesday February 9, 2022
• Time: 7:00PM EST / 4:00PM PST
• Venue: Purcell Pavilion

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Want more CBB predictions like this?

To get more NCAA Basketball betting previews like you've just read for Louisville vs. Notre Dame, all you've gotta do is visit our College Basketball Betting News section. It's that easy – they're all there!

We use the power of predictive analytics to find edges in the markets so we can publish the most comprehensive CBB betting previews out there. We're able to do this by comparing our in-house probabilities against the sportsbooks' odds (aka Vegas odds) the minute they go live.

So, get ahead of the game and beat the 'books today – it's only a click away.