Louisville vs. North Carolina CBB Predictions and Odds - Feb 21, 2022

North Carolina and Louisville meet in College Basketball action at Dean Smith Center on Monday, starting at 7:00PM EST.

Dimers' free betting picks for Louisville vs. North Carolina, as well as our score prediction and best odds, are detailed below.

Who will win Louisville vs. North Carolina?

Using high-tech computer power and data, Dimers.com has simulated Monday's Louisville-North Carolina NCAA Basketball matchup 10,000 times.

Dimers' leading predictive analytics model, DimersBOT, gives North Carolina an 82% chance of getting the W against Louisville.

MORE: Louisville vs. North Carolina Simulated 10,000 Times

Point Spread, Moneyline and Over/Under

North Carolina is the -9 favorite versus Louisville, with -120 at FanDuel Sportsbook the best odds currently available.

For the underdog Louisville (+9) to cover the spread, FanDuel Sportsbook also has the best odds currently on offer at -102.

BetMGM currently has the best moneyline odds for North Carolina at -500, which means you can risk $500 to win $100, for a total payout of $600, if it gets the W.

Meanwhile, FanDuel Sportsbook currently has the best moneyline odds for Louisville at +390, where you can bet $100 to profit $390, earning a total payout of $490, if it wins.

The Over/Under is set at 144.5 with DraftKings Sportsbook, which currently has the best odds for the Over at -105, while PointsBet currently has the best odds for the Under at -105.

As always, check out all the legal sportbooks that are available in your state for the best College Basketball odds and lines.

According to DimersBOT, North Carolina (-9) is a 57% chance of covering the spread, while the 144.5-point Over/Under is considered an equal 50-50 chance of hitting.

MORE: Today's Best Bets for All Major College Sports

Best Bets for Louisville vs. North Carolina

• Spread: North Carolina -9 at -120 with FanDuel Sportsbook (57% probability)
• Moneyline: North Carolina at -500 with BetMGM (82% probability)
• Over/Under: Under 144.5 at -105 with PointsBet (50% probability)

Dimers' best bets are based on world-class simulations and wagering intelligence to bring you the best possible plays 24/7.

Louisville vs. North Carolina Score Prediction

Dimers.com's predicted final score for Louisville vs. North Carolina at Dean Smith Center on Monday has North Carolina winning 77-67.

Use our interactive widget below to see the latest Spread, Over/Under and Moneyline probabilities and odds for the game, and click or tap on See Matchup for more.

Dimers has full betting coverage of Monday's Louisville-North Carolina matchup, including pre-game predictions, computer picks, and live win probabilities.

Don't forget, DimersBOT updates regularly, so keep an eye on this article for any changes to our betting insights ahead of Louisville vs. North Carolina on Monday February 21, 2022.

Get a Risk-Free Bet for Louisville vs. North Carolina

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Simply click or tap on this exclusive FanDuel Sportsbook link and create a new account – it's easy and takes less than 2 minutes.

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Louisville vs. North Carolina 2022 CBB Game Info

When does North Carolina play Louisville in College Basketball?

• Date: Monday February 21, 2022
• Time: 7:00PM EST / 4:00PM PST
• Venue: Dean Smith Center

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What other CBB games are on tonight?

Louisville and North Carolina aren't the only two NCAA Basketball teams you can bet on tonight. DimersBOT never stops and we've got picks and top bets for each and every CBB matchup via our College Basketball Predictions page.

Not only do we provide with you top-notch predictions, but we also have recommended bets for the Spread, Over/Under and Moneyline. Sound good? Check it out now!