Louisville vs. Michigan State CBB Predictions and Odds - Dec 1, 2021

Michigan State and Louisville meet in College Basketball action at Jack Breslin Students Events Center on Wednesday, with tipoff at 7:15 PM EST.

Dimers' free betting picks for Louisville vs. Michigan State, plus game predictions and best odds, are detailed in this article.

Who will win Louisville vs. Michigan State?

Based on cutting-edge computer power and data, Dimers.com has simulated Wednesday's Louisville-Michigan State NCAA Basketball matchup 10,000 times.

Dimers' famous predictive analytics model, DimersBOT, gives Michigan State a 65% chance of defeating Louisville.

MORE: Louisville vs. Michigan State Simulated 10,000 Times

Point Spread, Moneyline and Over/Under

Michigan State is the -3.5 favorite versus Louisville, with -115 at DraftKings Sportsbook the best odds available.

For the underdog Louisville (+3.5) to cover the spread, FanDuel Sportsbook has the best odds on the market at -102.

FanDuel Sportsbook has the best moneyline odds for Michigan State at -184, which means you can risk $184 to win $100, for a total payout of $284, if it gets the W.

Meanwhile, BetMGM has the best moneyline odds for Louisville at +165, where you can bet $100 to profit $165, earning a total payout of $265, if it wins.

The Over/Under sits at 136.5 with DraftKings Sportsbook, which has the best odds for the Over at -110, while FanDuel Sportsbook has the best odds for the Under at -105.

As always, check out the sportsbooks you can bet with in your state for the best College Basketball odds and lines.

According to DimersBOT, Louisville (+3.5) is a 54% chance of covering the spread, while the Over/Under total of 136.5 points is considered an equal 50-50 chance of hitting.

MORE: Predictions for Every CBB Game

Best Bets for Louisville vs. Michigan State

• Spread: Louisville +3.5 at -102 with FanDuel Sportsbook (54% probability)
• Moneyline: Michigan State Win at -184 with FanDuel Sportsbook (65% probability)
• Over/Under: Under 136.5 at -105 with FanDuel Sportsbook (50% probability)

Louisville vs. Michigan State Score Prediction

Dimers.com's predicted final score for Louisville vs. Michigan State at Jack Breslin Students Events Center this Wednesday has Michigan State winning 70-66.

Use our dynamic widget below to see the latest Spread, Over/Under and Moneyline probabilities and odds for the game, and click or tap on See Matchup for more.

Dimers has full coverage of Wednesday's Louisville-Michigan State matchup, including pre-game predictions, top betting picks, and live win probabilities.

Remember, DimersBOT updates often, so check this article for any changes to our betting insights before Louisville vs. Michigan State on Wednesday December 1, 2021.

Louisville vs. Michigan State 2021 CBB Game Info

When does Michigan State play Louisville in College Basketball?

• Date: Wednesday December 1, 2021
• Time: 7:15 PM EST / 4:15 PM PST
• Venue: Jack Breslin Students Events Center

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