Louisiana-Lafayette vs. Louisiana-Monroe prediction: Louisiana-Lafayette favored to win men's college basketball matchup [12/20/2025]

Louisiana-Monroe will face Louisiana-Lafayette in men's college basketball action at Fant-Ewing Coliseum on Saturday, commencing at 3:00 PM ET.

Based on the latest simulation results, Dimers' proven college basketball model projects Louisiana-Lafayette as the most likely winner of the Louisiana-Lafayette vs. Louisiana-Monroe game.

This article offers an expanded analysis of Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

Louisiana-Lafayette vs. Louisiana-Monroe prediction: Who will win and cover?

Using innovative machine learning and data, we have simulated the outcome of Saturday's NCAA basketball matchup between Louisiana-Lafayette and Louisiana-Monroe 10,000 times as part of our men's college basketball predictions coverage.

Our leading predictive model currently gives Louisiana-Lafayette a 61% chance of beating Louisiana-Monroe. Our predicted final score has Louisiana-Lafayette winning 71-68.

According to our model, Louisiana-Lafayette (-1.5) has a 55% chance of covering the spread, while the over/under total of 137.5 points has a 54% chance of going over.

Louisiana-Lafayette vs. Louisiana-Monroe odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Louisiana-Lafayette vs. Louisiana-Monroe picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: