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Lakers vs. Thunder prediction: Oklahoma City favored to win Wednesday's NBA matchup [11/12/2025]

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Written by Dave Garofolo

Get Los Angeles Lakers vs Oklahoma City Thunder predictions for NBA Wednesday.

Los Angeles Lakers-Oklahoma City Thunder Predictions and Game Preview.
Los Angeles Lakers vs. Oklahoma City Thunder NBA prediction for Wednesday, November 12, 2025.

The Oklahoma City Thunder will square off with the Los Angeles Lakers in NBA action at Paycom Center on Wednesday, commencing at 9:30PM ET.

Based on updated simulations and today’s injury news, Dimers' advanced NBA model projects the Thunder as the most likely winner of the Lakers vs. Thunder game.

This article offers an expanded analysis of Wednesday's matchup, including an expanded look at the predicted score, best bets and picks.

Lakers vs. Thunder prediction: Who will win and cover?

As part of Dimers' NBA predictions coverage—and following a review of recent results—our pregame model has generated moneyline, spread, and over/under probabilities for Wednesday's clash between the Lakers and Thunder.

According to our model, the Lakers (+8) have a 53% chance of covering the spread, while the over/under total of 229.5 points has a 51% chance of staying under.

 

Lakers vs. Thunder odds

We have researched the best NBA odds in America for this game, which are listed here:

Bet Type Lakers Thunder
Spread +8 (-106) -8 (-114)
Moneyline +260 -310
Total o229.5 (-110) u229.5 (-105)

All odds are correct at the time of publication and are subject to change.

Lakers vs. Thunder picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Lakers +8 -106
Moneyline Lakers +260
Total Under 229.5 -105

According to our best NBA bets for Wednesday, the top play to make on this game is Lakers +8 at the spread.

 

Lakers vs. Thunder game-day updates and essential details

Wednesday's action between the Thunder and Lakers at Paycom Center is scheduled to commence at 9:30PM ET.

Conclusion

We predict the Thunder, with a 74% win probability, will likely beat the Lakers on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Lakers vs. Thunder insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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